conclusions the present investigation supports the use of the methanolic extract of a. maurorum as an antiviral drug in folk and modern medicine. this activity may justify its use as a source of natural compounds to control fmdv in infected animals. background foot and mouth disease (fmd) is an infectious disease of cloven-hoofed animals that has adverse economic impacts. given the prevalence o...

since, the most susceptible laboratory animal to foot–and–mouth disease virus (fmdv) is guinea pig, and then one milliliter of fmdv type (o) concentrations of 106-106.5 tcid50was inoculated intradermally (id) to 10 plantar surface of guinea pig (right side). guinea pig adapted virus has been prepared after generalization phase, and then one milliliter of virus was inoculated intradermally to 30...

case presentation we presented a case of tb lymphadenitis in association with celiac disease that mimicked kfd in a young child. conclusions celiac disease, also known as gluten-sensitive enteropathy and nontropical sprue, is an autoimmune disease with chronic inflammation of small intestine, which is associated with increased risk of tb infection. tb lymphadenitis can mimic kfd. therefore, in ...

Infectious bursal disease virus (IBDV) in turkeys may result in immunosuppression, and inability of turkeys to resist nonpathogenic or less pathogenic organisms. A total number of 120 day-old commercial male turkeys were purchased and blood samples were collected from 20 day-old turkeys, remaining 100 were divided into four equal groups and kept in separated rooms. Groups 1 and 2 were infected ...

background and aims: respiratory syncytial virus (rsv) infection is common in infants and young children. in infants younger than one year old it may cause bronchiolitis and pneumonia which requires hospitalization. accurate and rapid diagnosis of the disease will help proper treatment of the disease and prevents further complications. methods: specimen taken from respiratory tract of sick chil...

Infectious bronchitis (IB) and Newcastle disease (ND) are highly contagious and the most economically important diseases of the poultry affecting respiratory tract and causing economic losses in poultry industry throughout the world. In the present study, the simultaneous detection and differentiation of causative agents of these diseases were investigated using duplex-RT-PCR. RNA was extracted...

Maedi-Visna (MV) virus and caprine arthritis encephalitis (CAE) virus known as small ruminant lentiviruses (SRLVs) cause chronic diseases in susceptible animals. The main reservoirs of these viral agents are sheep and goat. In sheep, MV virus causes a disease as the same name of the virus. This is the first seroprevalence survey of SRLVs in sheep population of Khorasan-e-Razavi province in Iran...

High morbidity and mortality of influenza virus infection makes it an important disease world-wide. Mouse is a very well-studied animal model for this disease with similar manifestation to human disease. It would be desirable to induce mucosal as well as circulating immune responses to obtain protection from infection and to decrease the spread of the virus. Cell mediated immunity (proliferativ...

Background and Aims: NDV (Newcastle Disease Virus) is one of the viruses that cause disease in avian with severe economic losses in the poultry industry in many countries. Fusion protein (F) which plays a major role in the virus pathogenicity contains several regions that have a role in the fusion process. Mutation in the sequence of HR1 & HR2 regions of this protein prevents fusion of the viru...