The 24-hour urinary output of 3-methoxy-4-hydroxy mandelic acid (V.M.A.) has been determined in 20 normal adults, 150 hypertensive patients, and four cases of phaeochromocytoma. In this last group estimations of urinary catecholamines and total urinary methylated amines were also performed and the overall results have been compared with the urinary excretory pattern of catecholamines and their ...

This work describes a new extraction method with hollow-fiber liquid-phase microextraction based on facilitated pH gradient transport for analyzing hippuric acid and mandelic acid in aqueous samples. The factors affecting the metabolites extraction were optimized as follows: the volume of sample solution was 10 mL with pH 2 containing 0.5 mol·L-1 sodium chloride, liquid membrane containing 1-oc...

Abstract Unreported graft copolymer of Meth Acrylamide (MAam) and our previously prepared fully characterized chitosan nanoparticles (CNPs) as a starting substrate has been synthesized under nitrogen atmosphere using potassium chromate /mandelic acid unique redox pair. This was done to see the impact both CNPs with respect well-dispersed nano sized particles, large surface areas, biodegradabili...

Countercurrent membrane supported reactive extraction (MSRE) was studied for removal of carboxylic acids from aqueous streams with a PTFE capillary membrane. Analysis the mass transfer rates performed to support modeling process. Total coefficients ranging 2.0·10-7 4.0·10-7 m/s were obtained when extracting lactic acid 20 wt% tri-N-octyl amine in 1-decanol thicknesses 260 µm and 80 µm. The limi...

Patients with 22q11 deletion syndrome (22q11DS) have a high prevalence of psychiatric disorders and intellectual disability. At present the neurobiology underlying psychopathology in 22q11DS is still not understood. In the present study, we analyzed urinary serotonergic, dopaminergic and noradrenergic markers in 67 adults with 22q11DS. Levels of serotonin and the catecholamine metabolite homova...

A new family of Lewis basic 2-pyridyl oxazolines have been developed, which can act as efficient organocatalysts for the enantioselective reduction of prochiral aromatic ketones and ketimines with trichlorosilane, a readily available and inexpensive reagent. 1-Isoquinolyl oxazoline, derived from mandelic acid, was identified as the most efficient catalyst of the series, capable of delivering hi...

Pd-catalyzed C-H functionalization of mandelic acid and α-phenylglycine is reported. We have developed different protocols for the arylation, iodination, acetoxylation, and olefination of these substrates based on two different (Pd(II)/Pd(IV) and Pd(II)/Pd(0)) catalytic cycles. Four crucial features of these protocols are advantageous for practical applications. First, the α-hydroxyl and amino ...