BACKGROUND Medical devices can be useful in a variety of diseases, but few devices have been specifically approved for use in children. The 2007 Pediatric Medical Device Safety and Improvement Act was passed to stimulate pediatric device development. The current state of trial evidence underpinning the approval of pediatric devices remains poorly described. METHODS We identified all high-risk...

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Government mandates to disclose information are a standard response to problems of asymmetric information. We examine recent major U.S. regulations issued between 2008 and 2013 to identify disclosure mandates and look for quantitative assessments of their effectiveness in improving comprehension. We also reviewed the retrospective regulatory review reports of four federal agencies – prepared pu...

OBJECTIVE We measured clinicians' level of knowledge and attitudes regarding Department of Defense-mandated clinical preventive services (CPS) delivery and the barriers they believe prevent the delivery of CPS at a large U.S. Air Force referral medical center. METHODS Our survey listed a range of prescribed specific CPS and solicited reasons why providers believed that they could not be deliv...

The American Organization of Nurse Executives (AONE) recognizes the need for adequate nurse-staffing levels to ensure the quality of patient care delivered in hospitals and health systems throughout our nation. The number of patients for which a nurse can provide safe, competent and quality care is dependent upon multiple factors. Studies have concluded that nurse-staffing levels are a critical...

Outpatient commitment, although often viewed as merely an extension of inpatient commitment, is only one of a growing array of legal tools used to mandate treatment adherence. The authors describe various forms of mandated community treatment. People with severe and chronic mental disorders often depend on goods and services provided by the social welfare system. Benefits disbursed by represent...

Blocking of foreign Web content by Internet access providers has been a hot topic for the last 18 months in Germany. Since fall 2001 the state of North-RhineWestphalia very actively tried to mandate such blocking. This paper will take a technical view on the problems imposed by the blocking orders and blocking content at access or network provider level in general. It will also give some empiri...

Proteasome biology has taken central stage in cardiac physiology and pathophysiology. The molecular heterogeneity of proteasome subpopulations supports the specificity of proteasome function to degrade diverse substrate repertoires. Unveiling the dynamics of proteasome function should inspire new therapeutic strategies for combating cardiac disease.

BACKGROUND Alcohol consumption on college campuses is high, and often dangerous. College administrators have created policies to control alcohol consumption, but student body support or opposition of specific policies has been relatively unexplored. METHOD The current study examined the relations of alcohol policy support with gender and alcohol consumption. Mandated students (N=229; 44% wome...