A variety of clinical and histological presentations can accompany the evolution of malignant melanoma. Unusual cytological variants of malignant melanoma include balloon cell, signet ring cell, myxoid and other metaplastic changes. With the exception of a case of pemphigus-like changes associated with malignant melanoma in paraneoplastic pemphigus, acantholysis is not a common histopathologica...

Received: 2009­08­31; Accepted: 2010­02­08 Primary malignant ovarian melanoma, which is primarily transformed from ovarian mature teratoma, is rare [1,2] . Each component of ovarian mature teratoma can be transformed to malignant tumor, with the squamous carcinoma as the most common type accounting for about 80% , followed by adenocarcinoma , and those transformed to melanoma are rare [3] . We ...

Desmoplastic melanoma(DM) is a subtype of malignant melanoma, and there are very few reports on the occurrence this disease in oral region. Since DM mainly composed achromatic spindleshaped tumor cells, its clinical histopathological diagnoses difficult. However, immunohistochemical staining useful for diagnosis DM.

While the early detection of malignant melanoma is important and has been emphasized widely in the past few years, it is difficult to accomplish. The purpose of this study is to assess how well dermatologists recognize malignant melanomas in patients with naevi. Information from 9,121 patients visiting two dermatological clinics in Stockholm and diagnosed melanocytic naevi was linked with the S...

THE literature on malignant melanoma of the uveal tract is extensive but case reports of multiple malignant tumours of this type are infrequent. Freckles and naevi are present in approximately 50 per cent. of normal eyes and "are even more frequent and larger in eyes which also contain malignant melanoma of the uveal tract" (Hogan and Zimmerman, 1962). According to Reese (1956), when the malign...

Metastatic pancreatic malignant melanoma is considered to be a highly aggressive neoplasm, and only few metastasectomies for lesions originating from the skin or the ocular region have been reported. We report a case of resection of pancreatic metastasis of malignant melanoma originating from the nasal cavity. An isolated pancreatic tumor was detected in a 46-year-old man who had undergone prot...

background: the most frequently mutated tumor suppressor gene found in human cancer is p53. in a normal situation, p53 is activated upon the induction of dna damage to either arrest the cell cycle or to induce apoptosis. however, when mutated, p53 is no longer able to properly accomplish these functions. the aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

Cutaneous malignant melanoma is a type of skin cancer that you can die from. The number patients being diagnosed with the rising in most countries. About 4000 were Sweden 2018. risk dying from cutaneous very much dependent on thickness melanoma, measure given by pathologist after removing melanoma. increases increasing thickness. Most who are will have thin melanomas, i.e. 1 mm or thinner.

The clinical identification of amelanotic malignant melanoma (AMM) and hypomelanotic malignant melanoma (HMM) becomes difficult due to the lack of pigmentation and to the diverse clinical presentations. Dermoscopy is very useful in these cases, increasing the level of suspicion of malignancy. We report 4 cases of amelanotic malignant melanoma and hypomelanotic malignant melanoma with characteri...

As the incidence and already high mortality rates of malignant melanoma have been steadily increasing in recent decades, the early detection and excision of malignant melanoma have imposed as the most important task. Staging of malignant melanoma is determined according to the level of invasion (Clark level) and vertical thickness (Breslow scale). Besides operative therapy, which is the only ef...