Lignosus rhinocerotis (Cooke) Ryvarden (LR) or tiger milk mushroom has traditionally been used in Malaysia due to its abundant medicinal properties. The potential effects of LR on the male and female fertility teratogenicity were investigated rats. Male Sprague Dawley (10 rats/group) orally administered with 0, 250, 500 1000 mg/kg/day extract for 30 consecutive days. Female (5 received same tre...

according to iran’s folk medicine, camphor, a crystalline ketone obtained from essential oils of cinnamomum camphora, has both sexual behavior attenuating and enhancing properties. this study examined the effects of camphor on sexual behavior in male rats. twenty four sexually mature male sprague-dawley rats were randomly divided into 4 groups receiving daily i.p. injections of olive oil as veh...

Males are at greater risk for renal injury than females. This may relate to NOavailability because female rats have higher renal endothelial NO synthase (NOS) levels. Previously, we found susceptibility to proteinuria induced by NOS inhibition in male as compared to female rats. Dyslipidemia and hypercholesterolemia dosedependently decreased renal NOS activity and caused renal injury in female ...

Background: The present study examined the possible role of endogenous opioidergic system in effect of food deprivation on formalin-induced nociceptive behaviors in male and female rats. Also, we investigated the effect of food deprivation on the plasma level of beta-endorphin and sex hormones. Methods: Food was withdrawn 48 h prior to performing the formalin test, but water continued to be ava...

Dimethyl hydrogen phosphite (DMHP), an intermediate in the production of insecticides or herbicides, was administered by p.o. gavage for 2 yr to male Fischer 344/N rats and male and female B6C3F1 mice at doses of 0, 100, or 200 mg/kg and to female Fischer 344/N rats at doses of 0, 50 or 100 mg/kg. Dose related toxicity was seen in the lungs of treated male and female rats. The lung lesions were...

Various physiological parameters including level of sex steroids undergo alterations following chronic administration of morphine. In this study, the effect of chronic administration of morphine on phasic and tonic pain was studied in morphine-dependent male and female rats in the presence and absence of gonads using formalin test. In addition, for evaluation of differences in dependency, withd...

Differences in the composition and subcellular localization of heteroreceptors brain can trigger central nervous system diseases, including epilepsy autism. Protein-protein interactions between Dopamine Receptors (DRs) GLUN2A GLUN2B subunits are critical mechanisms that regulate dopamine glutamate coordinated signals. These may be involved pathophysiological predisposition epilepsy. We hypothes...

Female rats treated with deoxycorticosterone acetate (DOCA) and salt do not get as hypertensive as male DOCA-salt treated rats. The adrenal gland contributes to the development and maintenance of DOCA-salt hypertension in male rats. However, little is known about adrenal medullary function in DOCA-salt hypertensive female rats. This study tested the hypothesis that bilateral removal of the adre...

the purpose of this research was to determine the effect of two kinds of diet (zinc deficiency and iron deficiency) on some anthropometrical indexes (body weight and crown-rump length), brain growth and motor function in young rats. adult male and female albino wistar rats were obtained from the breeding colony of pasteur institute, iran. the female albino rats were mated with normal male rats....

objective(s)ischemia-reperfusion injury (iri) is a leading cause of kidney transplantation failure, and ischemic-preconditioning (ipc) is a protective method against the iri. in the present study, the defensive effect of ipc on rats’ kidney was investigated and more importantly the differences between two genders were appraised.materials and methodsthirty two wistar rats were randomly allocated...