The average age of humans at their first infection with Plasmodium falciparum is typically less than 1 year in most endemic areas. This has been interpreted as evidence of the high transmissibility of the parasite, with the implication that control of malaria will require high levels of coverage with a potential vaccine. This interpretation is challenged by mathematical models that demonstrate ...

Though preventable, malaria is still one of the major public health problems worldwidemostly in low and middle income countries (1-4). In 2013, malaria killed over a billion people, mostly in sub-Saharan Africa (5). In 2015, there were over 200 million new cases and more than 400,000 malaria-related deaths around the globe (4). Over three-quarter of the Ethiopian territory is malarious indicati...

We report the resistance to 12 insecticides of specimens of Anopheles sacharovi, both in laboratory cultures and those collected in the malarious areas of Adana, Adiyaman, Antalya, Aydin, and Muğla in southern Turkey. Mortality was higher 24 h after exposure than immediately after exposure but was unaffected by temperature (24 degrees C or 29 degrees C) or the position of the test kit (horizont...

The human genome has been subjected to selective pressures to resist to infectious agents in spite of a heavy segregational load. With this regard, thalassaemia and glucose-6-phosphate dehydrogenase deficiency have been considered an efficient genetic protection against P. falciparum malaria in Sardinia, insular Italy1,2. In this island, some multiple sclerosis (MS)-associated HLA haplotypes ha...

By G. C. Roy, M.D., F.R.C.S., Inspecting Medical Office)'. It is seldom that an Inspecting Medical Officer has time to keep any important case under his direct observation from its commencement to tho end. He is hurried over in the course of his business from one extremity of his circle to the other, overlooking the clinical records of interesting instances of disease and cure, which are brough...

The drying of saturated soil, and the occurrence of socalled malarious disease, have, from very early periods, been connected as cause and effect; and that invisible, imponderable, chemically unrecognizable agent we call malaria, has been supposed to be more freely evolved the greater the ground saturation. Thus drying marshes have been esteemed more unhealthy than either ground covered altoget...

   Malaria is one of the worldwide parasitic diseases which threaten the life of hundreds of millions of people at the malarious areas each year. The emergence of chloroquine-resistant strains of Plasmodium falciparum in most of the malarious areas has encountered the relevant countries with some difficulties about treating the acute cases of the disease particulary if the monotherapy regimen h...

   Malaria is one of the worldwide parasitic diseases which threaten the life of hundreds of millions of people at the malarious areas each year. The emergence of chloroquine-resistant strains of Plasmodium falciparum in most of the malarious areas has encountered the relevant countries with some difficulties about treating the acute cases of the disease particulary if the monotherapy regimen h...

BACKGROUND Information about malaria risk factors at high altitudes is scanty. Understanding the risk factors that determine the risk of malaria transmission at high altitude villages is important to facilitate implementing sustainable malaria control and prevention programs. METHODS An unmatched case control study was conducted among patients seeking treatment at health centers in high altit...