Effect of ginger (Zingiber officinale R.) on metiram-inhibited spermatogenesis and induced apoptosis in albino miceSaber A. Sakr, Gamal M. Badawy

I investigated the seasonal testicular histology and acystic lobular spermatogenesis in Western Lesser Siren, Siren intermedia nettingi, from periodic sampling of this salamander over a span 21 yr (1994-2015) northeastern Arkansas. My results include following general findings: 1) largest lobules occurred primarily January-February during spermiogenesis spermatozoa maturation; 2) regression spe...

BACKGROUND Irradiation or chemotherapy that suspend normal spermatogenesis is commonly used to treat various cancers. Fortunately, spermatogenesis in many cases can be restored after such treatments but knowledge is limited about the re-initiation process. Earlier studies have described the cellular changes that happen during recovery from irradiation by means of histology. We have earlier gene...

We showed previously that testosterone (T) alone could induce spermatogenesis and produce normally fertile spermatozoa in the absence of circulating gonadotropins. These studies used the hpg mouse, which is characterized by a congenital gonadotrophin deficiency due to a major deletion in the GnRH gene. Administering T by a subdermal implant of a SILASTIC brand tube impregnated with crystalline ...

background: male infertility is a multifactorial disorder, which affects approximately 10% of couples at childbearing age with substantial clinical and social impact. genetic factors are associated with the susceptibility to spermatogenic impairment in humans. recently, sept12 is reported as a critical gene for spermatogenesis. this gene encodes a testis specific member of septin proteins, a fa...

objective: animal model studies have shown that msy2 and jhdm2a genes have an important role in spermatogenesis process and fertility of male mice. but the potential role of these genes in human spermatogenesis and fertility is not known yet. therefore, we evaluated expression ratios of these genes in testis tissues of men with normal and impaired spermatogenesis. materials and methods: in this...

OBJECTIVE Animal model studies have shown that MSY2 and JHDM2A genes have an important role in spermatogenesis process and fertility of male mice. But the potential role of these genes in human spermatogenesis and fertility is not known yet. Therefore, we evaluated expression ratios of these genes in testis tissues of men with normal and impaired spermatogenesis. MATERIALS AND METHODS In this...

Fragments of testis tissue from immature animals grow and develop spermatogenesis when grafted onto subcutaneous areas of immunodeficient mice. The same results are obtained when dissociated cells from immature testes of rodents are injected into the subcutis of nude mice. Those cells reconstitute seminiferous tubules and facilitate spermatogenesis. We compared these two methods, tissue graftin...

Spermatogenesis, the formation of sperm, is a complex developmental process that begins with the mitotic proliferation of spermatogonia and proceeds through extensive morphological changes that convert the haploid spermatid into a mature, functional spermatozoon. Although the process of spermatogenesis is the same in both mammalian and nonmammalian vertebrates, its control mechanisms are not we...