Novel biomimetic surfactants based on cholesterol as the hydrophobic segment and poly[2-(methacryloyloxy)ethyl phosphorylcholine] (pMPC) as the hydrophilic segment were synthesized in the present study by atom transfer radical polymerization (ATRP) of 2-(methacryloyloxy)ethyl phosphorylcholine (MPC) using a cholesterol-based macroinitiator. The association behavior of cholesterol-block-poly[2-(...

Controlled radical polymerization has proven to be a viable route to obtain polymers with narrow polydispersities (PDI’s) and controlled molecular weights under simple reaction conditions. It also offers control over the chain‐ends of the synthesized polymer. Atom transfer radical polymerization (ATRP) is the most studied and utilized of these techniques. In this study ATRP has ...

A polypeptide hybrid double hydrophilic diblock copolymer (DHBC), poly( N-isopropylacrylamide)- b-poly( l-glutamic acid) (PNIPAM- b-PLGA), was synthesized via the ring-opening polymerization of gamma-benzyl- l-glutamate N-carboxyanhydride (BLG-NCA) using monoamino-terminated PNIPAM as the macroinitiator, followed by deprotection of benzyl groups under alkaline conditions. Containing a thermores...

The self-organization of amphiphilic block copolymers in water strongly depends on their molecular structure, particularly their hydrophilic–hydrophobic balance. This study proposes tuning the amphiphilicity of block copolymers by a click strategy. This work prepares novel amphiphilic block-graft PCL-b-(PaN3CL-g-PBA) copolymers that comprise poly(e-caprolactone) (PCL) as the hydrophobic segment...

A novel type of pH-responsive biodegradable copolymer was developed based on methyloxy-poly(ethylene glycol)-block-poly[dopamine-2-(dibutylamino) ethylamine-l-glutamate] (mPEG-b-P(DPA-DE)LG) and applied to act as an intelligent nanocarrier system for magnetic resonance imaging (MRI). The mPEG-b-P(DPA-DE)LG copolymer was synthesized by a typical ring opening polymerization of N-carboxyanhydrides...

and the inability to tune the size of the features independent of the mold. Here, we seek to employ soft lithography to develop robust chemically bound coatings with microscale surface features of tunable heights. This paper describes the combination of soft lithographic molding and a surfaceinitiated polymerization (SIP) to produce a versatile process termed micromolding surface-initiated poly...

A series of peptide-based triblock copolymers cons i s t ing of poly(γ -benzy l -L -g lu tamate) -b -po ly (dimethylsiloxane)-b-poly(γ-benzyl-L-glutamate) [PBLG-bPDMS-b-PBLG] were synthesized using ring-opening polymerization (ROP). The chemical structure and degree of polymerizations were evaluated by H NMR. These triblock copolymers form thermoreversible gels in toluene with critical gel conc...