نتایج جستجو برای: m21
تعداد نتایج: 327 فیلتر نتایج به سال:
2-Ethylphenyl 4-(3-ethylureido)benzenesulfonate (SFOM-0046) is a novel anticancer agent that arrests cell cycle in S-phase and causes DNA replication stress leading to the phosphorylation of H2AX into γ-H2AX. First, using the M21, HT29, HT-1080 and HeLa cell lines, we confirmed that S-phase cell cycle arrest and γ-H2AX foci induction by SFOM-0046 is a general mechanism occurring in diverse canc...
Implementation of uranium bioremediation requires methods for monitoring the membership and activities of the subsurface microbial communities that are responsible for reduction of soluble U(VI) to insoluble U(IV). Here, we report a proteomics-based approach for simultaneously documenting the strain membership and microbial physiology of the dominant Geobacter community members during in situ a...
The time-dependent (1-72-h) spatial distribution of three biotinylated anti-melanoma monoclonal antibodies (MAbs), a control MAb, and several macromolecular tracers was studied in two small (4-12-mg), well-characterized human melanoma xenografts (SK-MEL-2, M21) growing in the s.c. space of athymic nude mice. The specific MAbs (436, IND1, and 9.2.27) recognize two different melanoma cell surface...
The German public sector is confronted with drastically increasing household deficits. Yet, a coherent concept of reorganizing public enterprises and administrations does not seem to be being applied, At the same time, economic models often appear too abstract or too complicated to be applied by practicioners. Some general guidelines must therefore be developed that are in line with economic re...
OBJECTIVES The alpha(v)beta(3) integrin is a cell adhesion molecule known to be involved in stages of angiogenesis and metastasis. In this study, the chelators CB-TE2A and diamsar were conjugated to cyclic RGDyK and RGDfD and the biological properties of (64)Cu-labeled peptides were compared. METHODS CB-TE2A-c(RGDyK) and diamsar-c(RGDfD) were labeled with (64)Cu in 0.1 M NH(4)OAc (pH=8) at 95...
Performance pay, at least as usually understand, is no good idea for non-executive directors. They have to supervise and control or in some situations even to fire and replace the executive managers. This means that their performance as supervisors is totally different from the performance of the supervised executive managers and even the company at large. Moreover, they are mostly interested i...
The observation of atmospheric neutrinos (See, e.g., Ref.[1]) and solar neutrinos (See, e.g., Ref.[2, 3]) gives the information on the mass squared differences and the mixings, which can be written in the three flavor framework of neutrino oscillations as (|∆m32|, θ23) and (∆m21, θ12), where I have adopted the standard parametrization [4] for the 3× 3 MNSP [5, 6] matrix. On the other hand, the ...
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