A novel dual tablet formulation for oral administration using xanthan gum as the carrier and meloxicam as a model drug has been investigated for colonspecific drug delivery using invitro methods. The tablets were evaluated for hardness, thickness, drug content uniformity, and were subjected to invitro drug release studies under conditions mimicking mouth to colon transit and the results of whic...

The successful production of new, safe, and effective vaccines that generate immunological memory is directly related to adjuvant feature, which is responsible for increasing and/or modulating the immune response. Several compounds display adjuvant activity, including carbohydrates. These compounds play important roles in the immune response, as well as having biocompatible properties in vaccin...

Genes required for xanthan polysaccharide synthesis (xps) are clustered in a DNA region of 13.5 kb in the chromosome of Xanthomonas campestris. Plasmid pCHC3 containing a 12.4-kb insert of xps genes has been suggested to include a gene involved in the pyruvylation of xanthan gum (N.E. Harding, J.M. Cleary, D.K. Cabañas, I. G. Rosen, and K. S. Kang, J. Bacteriol. 169:2854-2861, 1987). An essenti...

Title of Document: OPTIMIZATION OF XANTHAN CHITOSAN POLYELECTROLYTIC HYDROGELS FOR MICROENCAPSULATION OF PROBIOTIC BACTERIA Pavan Kumar Soma, Doctor of Philosophy, 2011 Directed By: Associate Professor, Y. Martin Lo, Department of Nutrition and Food Science The effectiveness of microencapsulation system for targeted delivery of probiotics depends on its ability to protect cells from harsh gastr...

Xanthan gum is a polysaccharide that is widely used as stabilizer and thickener with many industrial applications in food industry. Our aim was to estimate the ability of Xanthomonas campestris ATCC 13951 for the production of xanthan gum by using whey as a growth medium, a by-product of dairy industry. X. campestris ATCC 13951 has been studied in batch cultures using a complex medium for the d...

The current study is an attempt to contribute for efficient and cost-effective substrates for xanthan gum production. In this context, the sugar cane molasses wastes can be used as a cheap substrate for xanthan gum production. Xanthan biopolymer production by a novel Xanthomonas campestris strain IBRC-M 10644 was optimized with statistical approaches. Based on the results ...

Sensory parameters of gluten-free bread depend on the amount and type of hydrocolloids used as gluten replacers, as this determines interactions between them and starch, which is the main component of dough. The evaluation of gluten-free breads supplemented with various amounts of guar gum, pectin and xanthan, proved that bread with addition of xanthan has higher volume in comparison with pecti...

Background Xanthan gum, a commercial microbial polysaccharide, has many industrial applications, including the tertiary recovery of oil, due to its unique rheological behavior (e. g. high viscosity at low concentrations, pseudoplasticity, solubility, stability over a wide range of pH values and temperatures, compatibility with many salts) [1]. Its production employs glucose or sucrose, which ra...

A bacterial exopolysaccharide from Aphanothece halophytica GR02 (AH-EPS) solubilised in buffered 1 M guanidine hydrochloride, GuHCl was studied using capillary viscometry, double gap viscometry, sedimentation velocity and sedimentation equilibrium using analytical ultracentrifugation. Results from capillary viscometry indicate that the exopolysaccharide is xanthan-like in its shear thinning pro...