Prior work has shown that mild alkaline hydrolysis of nuclei previously extracted with cold dilute acid and with lipid sol vents yielded not only the expected RNA nucleotides but also free adenine and guanine in amounts which varied in versely with the extent of preliminary lipid extraction. The nucleic acid of the nuclei was identified as the source of the free purines. The experiments describ...

The response of different tumours to radiation varies. This variation has been attributed to, among others, varying DNA repair capabilities The response of three tumour lines, differing in their sensitivities to radiation, namely, murine fibrosarcoma, lymphosarcoma and ascites, was studied by following the activities of enzymes known to be involved in DNA repair. The activities of poly (ADP-rib...