What are Collagenous and Lymphocytic Colitis? Collagenous and lymphocytic colitis are clinical and pathologic syndromes representing forms of microscopic colitis that affect the large intestine. Both disorders usually present in middle-aged patients in the fifth or sixth decade of life. Collagenous colitis primarily affects women. The predominance in the female to male population is 8:2. Lympho...

postsurgical hypothyroidism and its incidence has not been fully investigated. in this study, the incidence of hypothyroidism and its possible risk factors at shariati hospital was assessed. one hundred and two patients with benign thyroid diseases, who had undergone thyroidectomy, were investigated with regards to thyroid function profile during period of one year after the operation every thr...

Three cases are presented of lymphocytic colitis with chronic diarrhoea concurrent with longterm use of Cyclo 3 Fort, a phlebotonic drug used in France. The histological and immunopathological features of lymphocytic colitis are described. We show that lymphocytic colitis is drug induced, particularly in one patient where the immunopathological features of mucosal immune cell activation were in...

A passage line of a spontaneous hamster fibrosarcoma is contaminated by the virus. of lymphocytic choriomeningitis. Tumors from animals receiving implants when newborn contain high titers of infectious lymphocytic-choriomeningitis virus and complement-fixing antigen, and hamsters receiving implants when weanlings develop high titers of complement-fixing antibody against lymphocytic-choriomening...

et al. Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia. Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease. a multicenter, international, phase 2 study of alvocidib for patients with fludarabine-refractory chron...

BACKGROUND The malignant B cells in chronic lymphocytic leukemia receive signals from the bone marrow and lymph node microenvironments which regulate their survival and proliferation. Characterization of these signals and the pathways that propagate them to the interior of the cell is important for the identification of novel potential targets for therapeutic intervention. DESIGN AND METHODS ...

IL-2 mediates the regression of certain malignancies, but clinical use is limited because of associated toxicities, including parenchymal lymphocytic infiltration with multiple organ failure. Secondarily induced cytokines are important mediators of IL-2 toxicity and IL-2-induced lymphocyte-endothelial adherence and trafficking. The recently discovered C-C chemokines, RANTES (regulated on activa...

C HRONIC LYMPHOCYTIC LEUKEMIA is a rare disease in Japan. Since the Atomic Bomb Casualty Commission ( ABCC ) initiated its leukemia case-detection program in 1950 only a few patients with this disorder have been identified in the cities of Hiroshima and Nagasaki. In this report the incidence of chronic lymphocytic leukemia during a 20 year period in both Hiroshima and Nagasaki is compared with ...