background : interleukin (il)-4 is a member of t helper 2 (th2) axis produced by t-lymphocyte and mast cell. it has been shown that il-4 expression changes in tumor tissues. the main objective of this study is to investigate the expression of il-4 mrna in patients with laryngeal squamous cell carcinoma (lscc) with or without lymph node involvement. materials and methods: mrna expression of il-4...

background: the role of diagnostic pathology has become more prominent. this study aimed to compare the accuracy of frozen section compared with permanent section in the morning and afternoon working hours. methods: in this cross-sectional study, 99 patients with stage 1 and 2 breast cancer who underwent sentinel and non-sentinel lymph node biopsy between 2013 and 2015 were included. the result...

background and objective: fine needle aspiration cytology (fnac) is a well-established method of diagnosis in palpable masses of various sites. this study was conducted to evaluate the usefulness of fnac as a diagnostic tool in the management of patients with cervical lymphadenopathy. patients and methods: totally 178 patients admitted to loghman-hakim hospital , tehran, iran, with cervical mas...

the charts of 27 patients with kawasaki disease (kd) admitted to nemazee hospital in shiraz from january 1991 to october 1998 were reviewed to identify the results of mean peroxidase index (mpxi) values, a measure of neutrophil staining intensity, obtained by the technicon hi analyzer (technicon instruments corp., tarrytown, ny) within the first 10 days of the illness 2 separate groups of patie...

  Schwannomas are benign nerve sheath tumors that originate from any anatomical site. Most of the schwannomas are found in the head, neck or limbs. Schwannoma arising in a lymph node is extremely rare. We have found only four cases in the review of the literature. We experienced a case of intranodal schwannoma in a perigastric lymph node. A 72 year-old female underwent cholecystectomy due to ...

Introduction: Medullary thyroid cancer (MTC) is an uncommon neoplasm originating from parafollicular C cells. Distant metastasis in MTC, such as axillary node involvement, is extremely rare.  Case Report: The present study describes a known case of MTC with axillary lymph node metastasis in a 31-year-old woman. In 2010, she underwent total thyroidectomy and right-sided modified radical neck dis...

  Introduction: Sentinel lymph node biopsy is the standard procedure for lymph node staging in intermediate thickness melanoma. In Iran, this procedure has not been addressed sufficiently. In this study, we report our experience in this area. Methods: Ten consecutive patients with intermediate thickness melanoma where included in our study. 1.5 mCi of Tc-99m antimony...

introduction: sentinel lymph node biopsy is the standard procedure for lymph node staging in intermediate thickness melanoma. in iran, this procedure has not been addressed sufficiently. in this study, we report our experience in this area. methods: ten consecutive patients with intermediate thickness melanoma where included in our study. 1.5 mci of tc-99m antimony sulfide colloid in two divide...

Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1)  and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...

Background: Cervical cancer is the second most common type of cancer among women. Effective screening programs can help cancer detection in early phases and reduce death. Metastasis to lymph nodes is one of the most prognostic factors in patients who underwent surgery. Also, a positive result from pathology report alert oncologist as a cause of death. Sentinel lymph node biopsy has been widely ...