Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...

the primary carcinoma may secondarily invade bone tissue through direct extensions, blood circulation or lymphatic transportation particulary when it is arising from breast, prostate, kidney, thyroid and lung. metastatics tumors of bone are more common than primary tumor of bone. the most common tumor, which metastasizes into bone, is the breast adenocarcinoma. some metastatic tumors of bone in...

bronchial leiomyoma is extremely rare. to date less than 60 cases have been reported in the world literature. the presented case here is a 30 year old woman who had been treated for bronchial asthma for several years. her chest radiograph showed bulluos emphysematous changes in the right lung and computer tomography scan found the tumor in the right main bronchus near carina. diagnosis was made...

Obesity is correlated with increased incidence of breast cancer metastasis; however, the mechanisms underlying how obesity promotes metastasis are unclear. In a diet-induced obese mouse model, enhanced lung in both presence and absence primary mammary tumors recruitment myeloid lineage cells into lungs. tumors, mice demonstrated numbers elevated collagen fibers within stroma, reminiscent premet...

A discrete MIBI avid lung lesion was found in cinematic views of myocardial perfusion imaging (MPI) of a 59 year-old woman. Interestingly, the abnormal uptake in the lung was detectable only in the rest phase images and not in the images acquired in the stress phase. MPI was performed for pre-operation cardiac risk assessment before correction surgery for spinal canal stenosis.  She had no...

a discrete mibi avid lung lesion was found in cinematic views of myocardial perfusion imaging (mpi) of a 59 year-old woman. interestingly, the abnormal uptake in the lung was detectable only in the rest phase images and not in the images acquired in the stress phase. mpi was performed for pre-operation cardiac risk assessment before correction surgery for spinal canal stenosis.  she had no past...

Lung cancer is the foremost cause of related deaths in U.S. The relatively poor outcome lung patients stems from fact that tumor not considered context its microenvironment while treating patients. a heterogeneous disease composed genetically and phenotypically different cells as well constantly interact with each other. Currently, treatment guided by genetic alterations identified specimen, wh...