UNLABELLED The migration of pathogen-specific T cells into nonlymphoid tissues, such as the lung, is critical to control peripheral infections. Use of in vivo intravascular labeling of leukocytes has allowed for improved discrimination between cells located in the blood from cells present within peripheral tissues, such as the lung. This is particularly important in the lung, which is comprised...

Background: With increasing immunocompromised patients, fungal infections especially lung infection, have also increased. In this study, fungal contamination of the respiratory system in immunocompromised patients was evaluated. Methods: This descriptive cross-sectional study was conducted in immunocompromised patients suspicious of pulmonary infections referring to specialized lung clinic of ...

Chlamydia pneumoniae (CP) lung infection can induce chronic lung inflammation and is associated with not only acute asthma but also COPD exacerbations. However, in mouse models of CP infection, most studies have investigated specifically the acute phase of the infection and not the longer-term chronic changes in the lungs. We infected C57BL/6 mice with 5 × 10(5) CP intratracheally and monitored...

linguatula serrata is one of well-known members of pentastomida which infects both humans and animals. the aim of this study was to evaluate the prevalence of l. serrata in mesenteric lymph nodes, livers and lungs of goats slaughtered in tabriz area, iran. mesenteric lymph nodes (mlns), livers and lungs of 280 goats slaughtered in tabriz, north-west of iran were investigated for nymphs of l. se...

Murine gammaherpesvirus 68 (MHV-68) is a natural pathogen of mice which causes an acute lung infection and establishes a latent infection in B lymphocytes. In this paper we describe the infection in transgenic B cell-deficient (muMT) mice, to determine whether a latent infection can be established in a mouse lacking circulating B lymphocytes. Little difference was observed in the acute lung inf...

This study was to investigate the effect of intra-amniotic administration of pulmonary surfactant (PS) on lung maturation in conditions of experimentally induced premature rupture of membranes (PROM) and intrauterine infection of rabbits. To establish animal (rabbit) models of intrauterine infection caused by PROM, E. coli was intrauterinely injected in 24-and 26-day pregnant animals. Twenty he...

Pulmonary Echinococcus granulosus is a parasitic infection found worldwide. Patients usually present with cough and/or hemoptysis with pulmonary nodule (s). Rarely do they enlarge to such sizes as to present with dyspnea. We report two cases with the largest hydatid cysts of the lung reported up to date: one measuring 24.5 x 19 cm and the other 19.5 x 16.5 cm. These cysts were removed intac...

introduction: mycobacterial tuberculosis (tb) infection is a serious opportunistic infection in renal transplant patients. although tb is normally considered as an opportunistic infection of the early period, it can be diagnosed at any time. in this study four patients who suffered from tb were examined. cases report: among 200 patients who were monthly examined in sina hospital of tehran, tb w...

To understand the importance of quorum sensing in chronic Pseudomonas aeruginosa lung infection, the in vivo pathogenic effects of the wild-type P. aeruginosa PAO1 and its double mutant, PAO1 lasI rhlI, in which the signal-generating parts of the quorum sensing systems are defective were compared. The rat model of P. aeruginosa lung infection was used in the present study. The rats were killed ...