Lung function testing in children is an important part of assessment, diagnosis and monitoring of children with lung disease. Regular testing can also be used to evaluate lung growth, review the effects of treatment and assess the risks and benefits of specific clinical interventions. Such tests can also be useful in the pre-operative assessment of high risk patients undergoing surgical procedu...

inflammatory responses and innate immunologic reactions play an important role in the respiratory system. ex vivo lung perfusion (evlp) is considered a novel method in the evaluation and reconditioning of donor lungs prior to transplantation. however, evlp’s effect on inflammatory and metabolic markers of human lung tissue is unknown. this study investigated how the performance of evlp on brain...

abstract background prevalence of hereditary blood diseases such as sickle cell anemia, sickle thalassemia and thalassemia major are high in khuzestan province. sickle cell anemia and beta-thalassemia are predominantly common in iranian arabs. pulmonary complications account for a large proportion of morbidity and mortality in patients with and sickle cell disease. periodic lung function assess...

The production of colony-stimulating factors (CSF) is delicately controlled through a complex network of humoral and environmental factors. We have studied some of the mechanisms which regulate the production of CSF as compared to general protein synthesis in the lung tissue ill vitro. When lung tissue from mice was cultured for various times in serum free medium, the first detectable le...

background: chronic obstructive pulmonary disease (copd) is a chronic respiratory disease, which reduces the lung function and causes respiratory symptoms over time, and it is primarily associated with shortness of breath, cough and sputum production. roflumilast, which is a long-acting selective inhibitor, reduces the anti-inflammatory effect of the main symptoms of copd. the aim of this study...

the production of colony-stimulating factors (csf) is delicately controlled through a complex network of humoral and environmental factors. we have studied some of the mechanisms which regulate the production of csf as compared to general protein synthesis in the lung tissue ill vitro. when lung tissue from mice was cultured for various times in serum free medium, the first detectable level of ...

introduction: the respiratory system is both a route of entry and exit for toxins and injurious agents, as well as being a target for chemical substances and pathogens. therefore, an understanding of the structure and function of the migratory cell populations of pulmonary tissues including alveolar macrophages is central in a number of important disease processes. this study aimed to identify ...

Objective(s): The role of isoflavones in pulmonary structure and function during menopause is not well studied. Moreover, the important role of estrogen in the physiological function of respiratory system has been revealed. Genistein, as an isoflavone, mimics estrogenic in diabetic and ovariectomized rats. Here, we hypothesized that genistein would reverse changes in the protein expression leve...