The AccuLeaf mMLC featuring four multileaf-collimator (MLC) banks has been used for the first time for an experimental comparison of conventional two-bank with novel four-bank dynamic MLC tracking of a two-dimensional sinusoidal respiratory motion. This comparison was performed for a square aperture, and for three conformal treatment apertures from clinical radiotherapy lung cancer patients. Th...

The performance of several previously designed model series of test analytes has been tested to characterize in an objective, quantitative manner modern stationary phases for reversed-phase high-performance liquid chromatography (RP-HPLC) using quantitative structure-retention relationships (QSRRs). Three QSRR approaches and three respective series of test analytes recommended for studies of th...

The Moduleaf, an add-on miniature multileaf collimator (MMLC) for the Siemens Oncor linear accelerator, provides high resolution field shaping with a maximum inter-leaf leakage dose of 1.50% at 6 MV. However, beyond the maximum treatment field size, the distribution of leakage and scatter along the y axis is different from that of the x axis, with maximum leakage values of 1.53% and 0.39%, resp...

In an effort to facilitate drug discovery, computational methods for facilitating the prediction of various adverse drug reactions (ADRs) have been developed. So far, attention has not been sufficiently paid to the development of methods for the prediction of serious ADRs that occur less frequently. Some of these ADRs, such as torsade de pointes (TdP), are important issues in the approval of dr...

A. Keshav, K. L. Wasewar, S. Chand, and H. Uslu a Department of Chemical Engineering, National Institute of Technology (NIT), Raipur Chhattisgarh-492010 India Department of Chemical Engineering, Visvesvaraya National Institute of Technology (VNIT), Nagpur 440011 India Department of Chemical Engineering, Indian Institute of Technology (IIT) Roorkee, Uttarakhand 247667 India d Beykent University,...

The retention of fifty structurally different compounds has been studied using linear solvation energy relationships. Investigations were performed with the use of six various stationary phases with two mobile phases (50/50 % v/v methanol/water and 50/50 % v/v acetonitrile/water). Packing materials were home-made and functionalized with octadecyl, alkylamide, cholesterol, alkyl-phosphate and ph...