Extracellular physiological recordings are typically separated into two frequency bands: local field potentials (LFPs) (a circuit property) and spiking multiunit activity (MUA). Recently, there has been increased interest in LFPs because of their correlation with functional magnetic resonance imaging blood oxygenation level-dependent measurements and the possibility of studying local processing...

BACKGROUND Although recently introduced directional DBS leads provide control of the stimulation field, programing is time-consuming. OBJECTIVES Here, we validate local field potentials recorded from directional contacts as a predictor of the most efficient contacts for stimulation in patients with PD. METHODS Intraoperative local field potentials were recorded from directional contacts in ...

How the brain orchestrates the musculoskeletal system to produce complex three-dimensional movements is still poorly understood. Despite first promising results in brain-machine interfaces that translate cortical activity to control output, there is an ongoing debate about which brain signals provide richest information related to movement planning and execution. Novel results by Bansal and col...

The intra-cortical local field potential (LFP) reflects a variety of electrophysiological processes including synaptic inputs to neurons and their spiking activity. It is still a common assumption that removing high frequencies, often above 300 Hz, is sufficient to exclude spiking activity from LFP activity prior to analysis. Conclusions based on such supposedly spike-free LFPs can result in fa...

18 We present a Recurrent Neural Network using LSTM (Long Short Term 19 Memory) units that is capable of modeling Local Field Potentials. We train 20 and test the network on real data recorded from patients. We construct 21 networks that are capable of modeling LFPs in single and multiple channels, 22 and can also model LFP dynamics after stimulation. 23 24

Local field potentials (LFP) reflect the properties of neuronal circuits or columns recorded in a volume around a microelectrode (Buzsáki et al., 2012). The extent of this integration volume has been a subject of some debate, with estimates ranging from a few hundred microns (Katzner et al., 2009; Xing et al., 2009) to several millimeters (Kreiman et al., 2006). We estimated receptive fields (R...

The spatial organization of tuning properties of neurons in the primate motor cortex is still unknown. Here, we analyze the directional tuning of neurons and local field potentials recorded in the motor cortex of monkeys performing center out arm movements. We found that the tuning of nearby neurons, and of single neurons and local field potentials recorded from the same electrodes is more simi...