Objective: Diazinon causes oxidative stress and dysfunction of the liver. This study was undertaken to evaluate the effects of the hydroalcoholic extract of Terminalia chebula, on some biochemical and histopathological parameters of liver tissue in diazinon-administered rats. Materials and Methods: Wistar rats were orally administered with 25 mg/kg body weight diazinon. Vehicle (distilled water...

In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...

The present study appraised the hepatoprotective activity of aqueous extract of Camellia sinensis leaves and its possible mechanism of action against carbon-tetrachloride-induced liver damage. Liver damage was induced by   intraperitoneal administration of equal mixture of carbon tetrachloride   and olive oil (50 % v/v, 0.5 ml/kg ) in male Wistar rats (150-220g) once daily for...

the present study appraised the hepatoprotective activity of aqueous extract of camellia sinensis leaves and its possible mechanism of action against carbon-tetrachloride-induced liver damage. liver damage was induced by   intraperitoneal administration of equal mixture of carbon tetrachloride   and olive oil (50 % v/v, 0.5 ml/kg ) in male wistar rats (150-220g) once daily for 7 days and the ex...

Background: Liver is a complex organ, essential for iron metabolism in the body and recognised as primary site synthesis of iron-related plasma proteins. also regulates concentrations an effective manner identifies changes systemic requirements. Haematological abnormalities are often associated with chronic liver diseases. Raised stores shows high response to infection hepatitis C, resistance i...

Introduction: Non-alcoholic fatty liver disease (NAFLD) is associated with oxidative stress, inflammation, and decrease in peroxisome proliferator-activated receptor alpha (PPAR-α) expression. Nitrochalcone is effective ingredient of chalcones with anti-inflammatory, anti-cancer and anti-hyperglycemic properties. This study examined the effect of intraperitoneal (IP) administration of nitrochal...

AIM To optimise the method of real-time elastography (RTE) in the assessment of liver fibrosis using an in-house prepared method for elastogram analysis, as well as a semiquantitative analysis based on newly introduced parameters. MATERIAL AND METHODS Sonoelastography was performed in 94 patients with various degrees of liver fibrosis and also in 25 healthy volunteers. As a reference method f...

OBJECTIVE A retrospective study to determine the relationships between platelet parameters and inflammation and fibrosis of the liver in patients with chronic hepatitis B virus infection (CHB). METHODS Patients with liver biopsy-confirmed CHB were included in the study. Liver fibrosis and inflammation were assessed by histopathology of biopsied liver tissue. Platelet count (PLT), platelet dis...