The inhibitory activity of liver extracts on thymidine incorporation into DNA was markedly enhanced by manganese and zinc. Manganese-activated liver extract (Mn-liver extract) also inhibited incorporation of deoxycytidine and adenine into DNA. The Mn-liver extract had no effect on incorporation of thymidine-5'-triphosphate into DNA but blocked the phosphorylation of deoxythymidine. The phosphor...

The inhibitory activity of liver extracts on thymidine incorporation into DNA was markedly enhanced by manganese and zinc. Manganese-activated liver extract (Mn-liver extract) also inhibited incorporation of deoxycytidine and adenine into DNA. The Mn-liver extract had no effect on incorporation of thymidine-5'-triphosphate into DNA but blocked the phosphorylation of deoxythymidine. The phosphor...

objectives: liver is one of the most sensitive tissues to oxidant damage. hence, the present study was conducted to compare the effects of melissa officinalis (mo) extract and atorvastatin on the activity of liver enzymes in rats. materials and methods: in this experimental study, 60 male wistar rats were selected and allocated to six groups (n=10). the control group received a normal diet, sha...

Introduction: Silymarine extract is currently prescribed by some physicians for treatment of fatty liver disease. In the present study, the effect of administration of tablet containing silymarine extract on plasma homocysteine (Hcy), folate, vitamin B12 and liver enzymes activity in non-alcoholic steatohepatitis (NASH) was investigated. Materials and Methods: Seventy-four patients (40 female a...

Objective: Chronic ethanol consumption has significant negative effects on liver tissue. Mechanisms of ethanol toxicity include oxidative stress and inflammation. The antioxidant and anti-inflammatory properties of the lemon verbena have been proven in studies. The aim of this study was to evaluate the protective effect of hydro alcoholic extract of Aloysia citriodora (AC) on ethanol-induced he...

Hepatoprotective activity of the ethyl acetate extract of Teucrium polium L. was investigated using rats with CCl4-induced liver damage. Specific biochemical parameters (glutathione peroxidase, superoxide dismutase, reduced glutathione and total antioxidative status) were estimated in blood and in liver homogenate. Lipid peroxidation in CCl4-intoxicated rats was evidenced by a marked increment ...

Mammea africana Sabine (Guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. The hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, to...

The aim of this study was to investigate the effective concentration of ethanolic extract  of bee pollen on liver, spleen and heart tissues of fish. Bee pollen extract in various concentrations (0.5, 2.5, 5, 10, 20 and 30 ppm) was administered to fish for 96 h under aquarium conditions. The malondialdehyde (MDA) levels, total antioxidant status (TAS), total oxidant status (TOS), oxidative stres...