The use of live bacteria to induce an immune response to itself or to a carried vaccine component is an attractive vaccine strategy. Advantages of live bacterial vaccines include their mimicry of a natural infection, intrinsic adjuvant properties and their possibility to be administered orally. Derivatives of pathogenic and non-pathogenic food related bacteria are currently being evaluated as l...

In the present study, 360 male day-old broiler chicks were used to determine the effect of mixed livevaccines of Newcastle disease (ND) and infectious bronchitis (IB) on serum and local antibody responses toIB. Chicks were randomly divided into 12 treatment groups of 3 replicates and reared for 40 days on floorpens. Groups 1 to 5 received mixed ND and IB vaccine. Groups 7 to 11 received IB vacc...

Limited effectiveness data are available comparing live attenuated influenza vaccine (LAIV) to inactivated influenza vaccine (TIV) among adults. To compare the incidence of influenza-like illness following immunization of adults with LAIV vs. TIV, we conducted a retrospective cohort analysis of active component U.S. military personnel for the 2005-2006 and 2006-2007 influenza seasons. Recruits ...

BACKGROUND It has been suggested that live attenuated influenza vaccine (LAIV) may be less effective in older individuals because of prior wild-type influenza infections. LAIV is currently approved in the United States, South Korea and Hong Kong for individuals 2-49 years of age. OBJECTIVE To examine data from previously published pediatric studies to determine the efficacy of LAIV in various...

The data show the percentage of children ‘fully immunised’ at 12 months, 24 months and 60 months, for 3-month birth cohorts of children assessed at the stated ages between 1 April and 30 June 2014 using ACIR data as at 30 September 2014. ‘Fully immunised’ refers to vaccines on the National Immunisation Program Schedule, but excludes rotavirus, varicella, and meningococcal C conjugate vaccines, ...

The data show the percentage of children ‘fully immunised’ at 12 months, 24 months and 60 months, for 3-month birth cohorts of children at the stated ages between July and September 2013 using ACIR data as at 31 December 2013. ‘Fully immunised’ refers to vaccines on the National Immunisation Program Schedule, but excludes rotavirus, varicella, and meningococcal C conjugate vaccines, and is outl...

INTRODUCTION Following the 2009 influenza A/H1N1 (pH1N1) pandemic, both seasonal and pH1N1 viruses circulated in the US during the 2010-2011 influenza season; influenza vaccine effectiveness (VE) may vary between live attenuated (LAIV) and trivalent inactivated (TIV) vaccines as well as by virus subtype. MATERIALS AND METHODS Vaccine type and virus subtype-specific VE were determined for US m...

Avian Pasteurella multocida is an agent of fowl cholera. The protective effect achieved through orthodoxvaccines is not ideal. The research on novel vaccines against avian Pasteurella multocida is imperative. Inthis study, the genes encoding outer membrane protein H and A (OmpH and OmpA) were cloned into theeukaryotic expression vector pcDNA3.1(+) and the recombinant plasmids, namely DNA vaccin...