LITHIuM, the lightest metal, has an atomic weight of seven and closely resembles sodium chemically. The ion is toxic and there are no therapeutic uses for lithium salts. Good (1903) quoted investigations of nearly twenty years previously in animals, where intravenous lithium salts depressed the heart's action and caused a fall in blood pressure. The dose of lithium salts necessary to stop the h...

In a study RBC-Plasma lithium ratios in manic patients treated with lithium we found that lithium responders had higher lithium ratios than lithium non-responders. There was, however, no cut off value which could differentiate lithium responders from non-responders.

Lithium cation is the charge carrier in lithium-ion battery. Electrolyte solution in lithium-ion battery is usually based on mixed solvents consisting of polar carbonates with different aliphatic chains. Despite various experimental evidences indicating that lithium ion forms a rigid and stable solvation sheath through electrostatic interactions with polar carbonates, both the lithium solvation...

the granites south of mashhad are located in the north-east of iran and occur in the suture zone between the binalud and kopeh dagh areas. these s-type granites are peraluminous with an upper triassic age and include intersecting pegmatites. these pegmatites are homogenous and show simple mineralogical combinations which include k-feldspars (microcline and orthoclase), plagioclase, quartz, mica...

Effect of high doses of lithium carbonate (40 rag/Kg.i.p. and p.o.) and lithium chloride (40 mg/Kg.i.p.) on renal and extra-renal functions were studied in normal male Charles Foster Strain of rats. Insignificant effect on urine output, creatinine clerance, sodium, potassium and lithium excretion was observed with these salts. Antidiuretic hormone levels were also not effected. However lithium ...

BACKGROUND No study has investigated when preventive treatment with lithium should be initiated in bipolar disorder. AIMS To compare response rates among patients with bipolar disorder starting treatment with lithium early v. late. METHOD Nationwide registers were used to identify all patients with a diagnosis of bipolar disorder in psychiatric hospital settings who were prescribed lithium ...

CONTEXT Prior observational studies suggest that treatment with lithium may be associated with reduced risk of suicide in bipolar disorder. However, these studies are biased toward patients with the most severe disorders, and the relation to sex and age has seldom been investigated. OBJECTIVE To investigate whether treatment with lithium reduces the risk of suicide in a nationwide study. DE...

Psychotropics (antipsychotics, mood stabilizers, antidepressants, anxiolytics, etc.) are commonly prescribed to treat Huntington's disease (HD). In HD preclinical models, while no psychotropic has convincingly affected huntingtin gene, HD modifying gene, or huntingtin protein expression, psychotropic neuroprotective effects include upregulated huntingtin autophagy (lithium), histone acetylation...

Owning to their very high theoretical capacity, lithium metal anodes are expected to fuel the extensive practical applications in portable electronics and electric vehicles. However, unstable solid electrolyte interphase and lithium dendrite growth during lithium plating/stripping induce poor safety, low Coulombic efficiency, and short span life of lithium metal batteries. Lately, varies of mic...

The incidence of biochemical hypothyroidism has been estimated to be as high as 30% in patients taking lithium (Lazarus et al., 1981). There are several different mechanisms involved. Lithium has been shown to block release of thyroxine from the thyroid gland (Spaulding et al., 1972) and probably also directly inhibits thyrotrophin-stimulated adenyl cyclase in the thyroid gland. Lazarus et al. ...