Phosphatidylinositol transfer proteins (PITPs) are believed to be lipid transfer proteins because of their ability to transfer either phosphatidylinositol (PI) or phosphatidylcholine (PC) between membrane compartments, in vitro. However, the detailed mechanism of this transfer process is not fully established. To further understand the transfer mechanism of PITPs we examined the interaction of ...

Based on data developed with the use of isolated lipid droplets from neonatal rat lung lipofibroblasts, we speculated previously that the droplet coat protein, adipose differentiation-related protein (ADFP), mediated the transfer of lipids into type 2 lung epithelial cells for the production of surfactant phospholipids. The present studies were designed to test the role of ADFP in this transfer...

abstract plant nonspecific lipid transfer proteins (nsltps) are divided into nsltp1 and nsltp2. the existence of an internal hydrophobic cavity, is a typical characteristic of nsltps that serves as the binding site for lipid substrates. in this communication a simple, rapid and low-cost alternative method was developed for purification of nsltp2 from rice paddy. after extracting, final supernat...

introduction: the use of exercise along with herbal supplements is one of the recommended methods for controlling obesity and its complications, but its effects have been controversial due to the diversity of training programs and also herbal supplements. hence, the objective of this study was to investigate the effects of 10 week ginger and progressive resistance training on c-reactive protein...

three experiments of 60 days duration were conducted in post larval stage of indian white shrimp, fenneropenaeus indicus, to explore the appropriate protein: lipid ratios in their diets. a common ingredient mixture consisting of; fish meal, shrimp meal, ground nut oil cake, cholesterol, lecithin, vitamins and minerals blended with chicken egg albumin, tapioca flour and cellulose (filler) was us...

background: the aim of the present study was to evaluate the radioprotective effect of grewia asiatica fruit pulp extract (gae) on swiss albino mice exposed to gamma radiation. in the present study radioprotective efficacy of grewia asiatica (rich in anthocyanin, carotenes, vitamin c, etc.) was studied against radiation induced biochemical alterations in mice cerebrum. materials and methods: fo...

Lipid-mediated transfection was compared to adenoviral-mediated gene transfer in COS-7 cells as well as human monocyte-derived macrophages (HMDM). For this purpose, we monitored enhanced green fluorescent protein (EGFP) expression by fluorescence microscopy and quantified gene transfer by competitive PCR. Transfection of COS-7 cells with a novel lipid formulation for DNA transfer was highly eff...

Microsomal triglyceride transfer protein (MTP) is a heterodimeric protein that transfers neutral lipids between membranes in vitro. Absence of this lipid transfer activity in the microsomes of abetalipoproteinemia patients established its pivotal function in lipoprotein assembly. Recent studies indicate that the lipid transfer activity is involved in importing triglycerides into the lumen of th...