The present study deals with exploration of lipid peroxidation induction capacity of flutamide, an anticancer drug, and in vitro evaluation of water extract of Spirulina platensis as a suppressor of flutamide-induced lipid peroxidation. Goat liver homogenate has been used as the lipid source. This evaluation was done by measuring the malondialdehyde and reduced glutathione content of the tissue...

Lipid peroxidation is a primary cause of quality deterioration in meat and meat products. Free radical chain reaction is the mechanism of lipid peroxidation and reactive oxygen species (ROS) such as hydroxyl radical and hydroperoxyl radical are the major initiators of the chain reaction. Lipid peroxyl radical and alkoxyl radical formed from the initial reactions are also capable of abstracting ...

The present study deals with exploration of lipid peroxidation induction capacity of cyclophosphamide, an anticancer drug, and in vitro evaluation of ascorbic acid as a suppressor of cyclophosphamide induced lipid peroxidation. Goat liver homogenate has been used as the lipid source. This evaluation was done by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric o...

objective: type 2 diabetes mellitus is a complex metabolic disorder with adverse cardiovascular risk. chromium (cr) is an essential nutrient and its role in carbohydrate and lipid metabolism has not been clarified especially in iran. the aim of this study was to evaluate the effect of chromium picolinate administration on blood glucose, hba1c, lipid profile and lipid peroxidation in type 2 diab...

objective(s): renal ischemia reperfusion (ir) contributes to the development of acute renal failure (arf). oxygen free radicals are considered to be principal components involved in the pathophysiological tissue alterations observed during renal ir. the purpose of this study was to investigate the effect of co-administration of melatonin (mel) and erythropoietin (epo), potent antioxidant and an...

background: non-steroidal anti-inflammatory drugs (nsaid) have been associated with antioxidant property and have been shown to improve the circulating antioxidant status on daily dosing in different inflammatory conditions. the present study was conducted to investigate the antioxidant role of meloxicam in aluminum induced oxidative stress in rat brain. methods: in the in vivo experiments, spr...

oxygen free radicals may be implicated in the pathogenesis of ischemia reperfusion damage. as the antioxidant effects of some species of pistacia have been reported, the protective effects of pistacia vera l. gum extract (0.1-0.5 g/kg) on oxidative damage following cerebral ischemia were studied in rats. ischemia was induced using four-vessel occlusion model and evaluated using measurement of m...

the side effects of synthetic antioxidants have been considered in different studies. accordingly, there is an increasing interest toward the use of natural substances instead of the synthetic ones. in this study, the aqueous and ethanolic extracts of pistacia vera leaves and fruits as well as hydroalcoholic extract of gum were tested for a possible antioxidant activity using in vitro methods. ...

due to the presence of polyphenols and phthalides in kelussia odoratissima mozzaf (umbelliferae; k. odoratissima hereafter), this medicinal plant might be a robust in-feed additive to modulate lipid peroxidation in meat-type chickens. the present study evaluates antioxidative, antihyperlipidemic, and growth-promoting effects of k. odoratissima in meat-type chickens. in a 37-day trial (5-42 days...

resistance of the weanling rat to acetaminophen (ap ap)-induced hepatotoxicity is manifested with regard to a surge in apap-glutathione (osh) conjugate formation in the liver [allameh et al. mech aging dev 95(1997)71]. the present study was conducted to assess the role of this detoxification pathway in apapinduced lipid per6xidationin the liver. lipid peroxidation measured as thiobarbituric aci...