A polyethylenimine adjuvant modified by mannose, which may be used in the study of vaccine adjuvant, was prepared this paper. Its structure characterized infrared spectroscopy and its micromorphology observed transmission electron microscopy. series mannose-modified polyvinylimine were according to molar ratio primary amine groups between mannose polyvinylimine, their storage stability at 4°C. ...

Positively charged polyelectrolytes hold significant potential as materials for creating antibacterial coatings. We examined the physicochemical and mechanical properties of macromolecules in water solutions coatings series branched polyethyleneimine (PEI) linear polydiallyldimethylammonium chloride (PDADMAC) with different molecular weights. The microbiological study was conducted to analyze b...

Immunosensors based on the microgravimetric quartz crystal microbalance (QCM) technique have been developed for the detection of Salmonella species from serogroups A, B and D. Salmonella serogroup-specific murine monoclonal antibodies, respectively, raised against these serogroups were immobilized onto the silver electrodes of piezoelectric (PZ) crystals by cross-linkage via glutaraldehyde (GA)...

The isolation of 3,6,9,12-tetraazatetradecane-l,14-diamine (linear isomer of pentaethylene­ hexamine, linpen) from a technical polyamine mixture is described. In methanol, linpen acts as a hexadentate ligand towards cadmium(II). The solid compounds [Cd(linpen)](BPh4)2 (1), [Cd(linpen)](BPh4)2-2DM SO (2) and [Cd(linpen)](BF4)2 (3) have been isolated and character­ ized by elemental analysis, spe...

Ferromagnetic carbon-coated cobalt nanoparticles have been ligated by a covalent or non-covalent strategy with dendrons or polymers bearing amino-, hydroxy- or polyether-functionalities, aiming at synthesizing materials that are dispersible in aqueous solutions, being a prerequisite for applications in biomedicine. Most efficiently for this purpose proved to be a covalently anchored polyethylen...

We report a direct method to amplify the exponential growth of multilayers significantly by the alternating deposition of polyethylenimine (PEI) at high pH and poly(acrylic acid) (PAA) at low pH. The alternating pH switches the degree of ionization of the polyelectrolytes in the multilayers, which enhances the diffusion of PEI into and out of the film and hence increases the deposited mass per ...

Here, we demonstrate an anion controlled molecular gate based on synthetic ion channels modified with polyethyleneimine. For single conical nanochannels, addition of ATP leads to significant decrease in the rectified ion flux, representing the closure of the ionic gate. Complementary experiments performed with nanoporous membranes show that the flux of charged dye (NDS(2-)) through a cylindrica...

Treatment of diseases on the molecular level by genetic material is limited by effective delivery mechanisms. We focused on the synthesis of a pH-sensitive gene delivery vehicle based on dimethylaminoethyl methacrylate (DMAEMA) with tunable swelling, cross-linking density, and DNA release kinetics within the endosomal pH range. Our strategy, which utilized a single step for DNA encapsulation, e...

A synthetic polymer, polyethyleneimine containing dodecyl (C(12)H(25))-chains for binding sites and imidazole moieties for functional catalytic groups, catalyzes the hydrolysis of phenolic sulfate esters by a two-step mechanism resembling that of the corresponding natural enzyme. Quantitative rate studies give kinetic parameters that show that the polymer (synzyme) accelerates the rate 10(12)-f...