Squamous cell carcinoma (SCC) is one of the most common cancers of the head and neck region worldwide and is generally treated surgically in combination with radiotherapy and/or chemotherapy. However, anticancer agents have numerous serious side effects, and alternative, less toxic agents that are effective as chemotherapeutics for SCC are required. The Paeoniaceae family is widely used in trad...

Advanced squamous cell carcinomas (SCC) of the skin can cause significant tissue destruction and may metastasize. Understanding the determinants of patient delay could help prevent advanced presentation. The purpose of the present study was to examine patient- and healthcare-related factors associated with delay before the detection and treatment of SCC. A sample of 308 patients with SCC treate...

Self-compacting concrete (SCC) is a highly efficient that can be compacted and formed under its own weight without external vibration. However, the constituents of SCC are many they have diverse material properties. Hence, it difficult to predict working performance with single factor regression relationship. Therefore, artificial neural network (ANN) approach chosen in present work simulate re...

Both retroviral infections as well as human tumors may cause immunosuppression. One of the factors involved in immunosuppression in patients with si11in11iniis cell carcinoma of the head and neck (SCC-HN) is a protein related to the retroviral protein pl5E. A conserved, 17-amino acid sequence represents the immunosuppressive epitope of retroviral plSE. In order to study the relationship between...

Understanding the determination of cell fate choices after cancer treatment will shed new light on cancer resistance. In this study, we quantitatively analyzed the individual cell fate choice in resistant UM-SCC-38 head and neck cancer cells exposed to cisplatin. Our study revealed a highly heterogeneous pattern of cell fate choices in UM-SCC-38 cells, in comparison to that of the control, non-...

Powder type of self-compacting concrete (SCC) needs high cement content to achieve self-compactibility, this will be undesirable in tropical climate Sudan due implication hydration heat. This paper investigates reducing up 340 Kg/m3 by blending limestone powder (LSP) 15 % as replacement weight. Therefore, fifteen mixes having maximum (P) 400 have been carried out with four water/powder ratios (...

BACKGROUND Conventional cancer therapy including surgery, radiation, and chemotherapy often are physically debilitating and largely ineffective in previously treated patients with recurrent head and neck squamous cell carcinoma (SCC). A natural photochemical, hypericin, could be a less invasive method for laser photodynamic therapy (PDT) of these recurrent head and neck malignancies. Hypericin ...

Introduction. It is rare for actinic or squamous cell carcinoma (SCC) in situ to metastasize. Case Presentation. A 67-year-old male had a significant medical history including severe psoriatic arthritis treated with UVB, methotrexate, and rapamycin. He had twenty-five different skin excisions of actinic keratosis four of which were invasive SCC. Our patient developed shortness of breath necessi...

Safingol, L- threo-dihydrosphingosine, induces cell death in human oral squamous cell carcinoma (SCC) cells through an endonuclease G (endoG) -mediated pathway. We herein determined whether safingol induced apoptosis and autophagy in oral SCC cells. Safingol induced apoptotic cell death in oral SCC cells in a dose-dependent manner. In safingol-treated cells, microtubule-associated protein 1 lig...

Self-compacting concrete (SCC) is a special type of that highly flowable, nonsegregating and spread into place by its own weight, completely filling the formwork even in presence dense reinforcement then encapsulating rebar without need for any additional compaction. This research was carried out to evaluate effects bentonite clay wheat straw ash as partial substitution cement SSC. Bentonite we...