نتایج جستجو برای: leukotriene antagonists
تعداد نتایج: 55425 فیلتر نتایج به سال:
BACKGROUND Perioperative bronchospasm refractory to β agonists continues to challenge anesthesiologists and intensivists. The TMEM16A calcium-activated chloride channel modulates airway smooth muscle (ASM) contraction. The authors hypothesized that TMEM16A antagonists would relax ASM contraction by modulating membrane potential and calcium flux. METHODS Human ASM, guinea pig tracheal rings, o...
Background: Cysteinyl leukotrienes (CysLTs) play a crucial role in the pathogenesis of airway remodeling. The use of CysLTs receptor antagonists has been included in the management of asthma and rhinitis. However, despite the action of these compounds on leukotriene production has been well documented, their role in airway remodeling remains unclear. Objective: We aimed to investigate the capab...
and commentary also appear in ACP Journal Club. Therapeutics EBM Volume 8 March/April 2003 49 www.evidence-basedmedicine.com group.bmj.com on June 22, 2017 Published by http://ebm.bmj.com/ Downloaded from
BACKGROUND : The aim of this study is to compare asthma controller therapy in children between Europe and Japan. MATERIALS AND METHODS : A questionnaire-based survey was conducted at the 2007 annual meeting of the European Respiratory Society held in Stockholm. In total, 120 answers were collected from European doctors. We divided Europe into 5 areas: South, West, North, East, and Central. Th...
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