Vitreous seeding is one of the primary reasons for treatment failure following conservative management of retinoblastoma.1,2 In our hands, until early 2006, most children with recurrent vitreous seeding were managed with plaque radiotherapy, external beam radiotherapy, or enucleation.1,2 In 2006, following the initial experience of Kaneko and Suzuki in Japan,3 we performed the first intravitrea...

Purpose: Ocular neoplasms, both primary and metastatic, may present with visual disturbance or vision loss often are asymptomatic. Clinical examination demonstrate leukocoria, abnormal pupillary light reflex, a mass lesion without retinal detachment hemorrhage. Retinoblastoma in children uveal melanoma ocular metastases adults the most important malignant neoplasms referred for imaging to aid d...

BACKGROUND This study presents magnetic resonance imaging (MRI) findings of both the anterior and posterior types of persistent hyperplastic primary vitreous (PHPV) to facilitate the differential diagnosis from other intraocular abnormalities. METHODS Seventeen patients with PHPV who were evaluated using non-contrast and contrast-enhanced T1- and T2-weighted images were retrospectively review...

PURPOSE To discuss the clinical characteristics, treatment and outcomes of germline and non-germline retinoblastoma tumors. METHODS A retrospective study was performed on retinoblastoma cases from 1979 to 2007. General characteristics of the patients, treatment modalities, histopathological findings and survival were compared in germline versus non-germline cases. RESULTS We analyzed 557 ca...

Purpose To report the clinical and histopathological findings of atypical intravitreal growth of a retinoblastoma with a multi-branching configuration. Observations A 7-month-old boy was referred to our hospital due to leukocoria in the right eye. Ophthalmic examinations identified multi-branching vessels surrounded by diaphanous tissue behind the lens in the right eye. Imaging modalities sho...

BACKGROUND Delay in diagnosis of retinoblastoma causes considerable parental distress; however, the primary healthcare professional (PHP) may have difficulty detecting the most common presenting symptom-leucocoria. Alternatively, the PHP may not appreciate that retinoblastoma is the pathology underlying more common ocular symptoms in infants and young children. METHOD The parents of 100 recen...

PURPOSE Protein C deficiency is an autosomal recessive disorder, which predisposes the patient to potentially blinding and widespread lethal thromboembolic complications, especially in the homozygous type. We here report the first Korean case of ophthalmic involvement and its surgical treatment in homozygous protein C deficiency. METHODS A 3.4kg, full term girl was born by normal delivery but...

AIM To assess main indications, postoperative complications and clinicopathological correlation of ocular enucleation-evisceration. METHODS A total of 107 subjects who underwent enucleation and/or evisceration and received hydroxyapatite implants (Scleral wrap or mesh) were assessed. For each patient clinicopathological data was collected which included demographic information, clinical histo...