Oxidative stress-related phenotypic changes and a decline in the number of viable cells are crucial contributors to intervertebral disc degeneration. The polyphenol epigallocatechin 3-gallate (EGCG) can interfere with painful disc degeneration by reducing inflammation, catabolism, and pain. In this study, we hypothesized that EGCG furthermore protects against senescence and/or cell death, induc...

Attempts to link physiological thermal tolerance global species distributions have relied on lethal temperature limits, yet many organisms lose fertility at sublethal temperatures. Here we show that, across 43 Drosophila species, better match male-sterilizing temperatures than This suggests that may be determined by limits reproduction, not survival, meaning underestimating the impacts of clima...

Daily temperature variation (DTV) is an important warming-related stressor that may magnify pesticide toxicity. Yet, it unknown whether the impact under DTV partly ameliorated by a faster degradation caused cyclically higher temperatures DTV. As synergisms be more likely energy-limiting conditions, of chlorpyrifos was tested on mosquito Culex pipiens in absence and presence interspecific compet...

Most of the studies on impact insecticides have always used acute toxicity with an indicator death, whereas lethal effect cannot fully determine insecticide insects. Overall, sublethal dose/concentration can cause biological effects, disrupt egg number, laying period, larva and pupal weight, development life span fertility rate, in addition to influencing feeding behavior, spawning locomotor sy...

The effect of sublethal, midlethal, and lethal doses of total-body X irradiation on the fecal microbial population of the rat was studied. No changes were observed in animals receiving sublethal doses of X ray. Midlethal and lethal doses produced an increase in the numbers of fecal coliforms, staphylococci, streptococci, and fungi; these changes were transient in rats that survived, but were mo...

Freshwater cat fish Clarias batrachus was exposed to Butachlor, Imidacloprid and Sodium fluoride with lethal and sub-lethal concentration for 72 hrs and 21 days durations. Protein changes in liver and muscles were analyzed after exposure period. Imidacloprid and sodium fluoride caused remarkable protein loss lethal concentration but at sub-lethal level their toxicity was moderate. But Butachlor...

An analysis of mammalian cell radiation-dose survival curves, based on the linear-quadratic formalism, is shown to yield insights in the various components of damage that contribute to cell reproductive death. RBE-LET relationships of single-track lethal damage, sublethal damage, potentially lethal damage and DNA double-strand breaks are compared. Single-track lethal damage is derived to be com...

the common green lacewing is an important natural enemy used for pest control in greenhouses. it is also very common in many agricultural systems. hence, studying lethal and sublethal effects of insecticides on this predator would be useful. toxicity of endosulfan, imidacloprid and indoxacarb was assessed on 1st instar larvae of chrysoperla carnea (stephens) in laboratory. residual bioassays we...