We describe LaueView, a code for processing the measured intensity data in Laue X-ray di raction experiments to obtain corrected structure amplitudes for each re ection that take account of the various distortion e ects. The resulting corrected intensity data can then be used to recover the molecular structure by isomorphous re nement or by solution of the phase problem. We describe the key num...

Felix Fernandez-Alonso,1,* Carlos Cabrillo,2,† Ricardo Fernández-Perea,2 Francisco J. Bermejo,3 Miguel A. González,4 Claudia Mondelli,5 and Emmanuel Farhi4 1ISIS Facility, Rutherford Appleton Laboratory, Chilton, Didcot, Oxfordshire OX11 0QX, United Kingdom 2Instituto de Estructura de la Materia, IEM-CSIC, Serrano 123, Madrid E-28006, Spain 3IEM-CSIC, Unidad Asociada de Fı́sica Aplicable, Depart...

Acetylcholinesterase (AChE) is one of nature's fastest enzymes, despite the fact that its three-dimensional structure reveals its active site to be deeply sequestered within the molecule. This raises questions with respect to traffic of substrate to, and products from, the active site, which may be investigated by time-resolved crystallography. In order to address one aspect of the feasibility ...

We propose a crystal configuration using a single Laue spherical crystal for imaging applications. A crystal in Laue geometry set to focus a divergent beam in the meridional (diffraction) plane, but does not focus in the sagittal plane. A transmission object placed in the beam is imaged with different horizontal and vertical aspect ratio, but it is possible to find a configuration with similar ...

Electron crystallography offers an increasingly viable alternative to X-ray crystallography for structure determination, especially for membrane proteins. The methodology has been developed and successfully applied to 2D crystals; however, well-ordered thin, 3D crystals are often produced during crystallization trials and generally discarded due to complexities in structure analysis. To cope wi...

We investigate electron vortex beams elastically scattered on chiral crystals. After deriving a general expression for the scattering amplitude of a vortex electron, we study its diffraction on point scatterers arranged on a helix. We derive a relation between the handedness of the helix and the topological charge of the electron vortex on one hand and the symmetry of the higher-order Laue zone...