Degenerative mitral valve disease is responsible for the syndromes of billowing mitral leaflet, mitral valve prolapse (MVP), floppy mitral valve, and flail leaflet. The pathology of these is mainly caused by myxomatous infiltration and fibroelastic deficiency. In the 1960s, Reid and Barlow and colleagues proposed that mid to late systolic clicks and apical late systolic murmurs were of mitral v...

obstructive cardiomyopathy. Br Heart J 32: 691, 1970 15. Barlow JB, Bosman CK, Pocock WA, Marchand P: Late systolic murmurs and nonejection (mid-late) systolic clicks. An analysis of ninety patients. Br Heart J 30: 203, 1968 16. Bon Tenpo CP, Ronan JA, deLeon AC, Twigg HL: Radiographic appearance of the thorax in systolic click-late systolic murmur syndrome. Am J Cardiol 36: 27, 1975 17. Solomo...

In this report, we describe a continuous murmur heard in a young woman at the beginning of her lactation period, which illustrates a typical example of 'Mammary Souffle', described one century ago. Colour Doppler and pulsed-wave mode echocardiogram allowed to precise, for the first time, the arterial nature of increased systolic and diastolic blood flow in tortuous branches of internal mammary ...

Mitral regurgitation and its haemodynamic features were investigated non-invasively in cases of hypertrophic cardiomyopathy by means of two dimensional Doppler echocardiography. There were 28 patients, 14 of whom showed systolic anterior motion (SAM) of the mitral echo; the other 14 did not. The following results were obtained. (1) Mitral regurgitation was detected by the Doppler technique in a...

Much has been written by physicians about patients referred to them because of the discovery of a systolic murmur. Inevitably such consultant physicians have scant opportunity to judge the incidence, character, and significance of murmurs among apparently healthy people. Freeman and Levine (1933) described the systolic murmurs that they had found in a group they had examined of a thousand perso...

Complications in patients with systemic lupus erythematosus (SLE) can lead to mortality (1). A 54-year-old woman with an 18-year history of SLE was admitted because of abdominal pain, vomiting, diarrhea, and mental confusion. A physical examination revealed a late systolic murmur and mild abdominal distension. Her complete blood count showed mild anemia and thrombocytopenia. The imaging studies...

The Attending Physician’s Statement (APS) confirms the history above. It also indicates that she has a normal build and a regular pulse. Blood Pressure is 120/80. A midsystolic click and 2/6 late systolic murmur are audible at the apex. 1991 chest x-ray is reported as normal. 1991 ECG reveals sinus rhythm with minor ST-T wave changes in leads 2, 3 and AVF. A 1990 echocardiogram report discloses...

The lady has a 12 18-month history of a progressive exertional dyspnea with chest tightness. Her heart rate was 68 per minute and blood pressure was 110/85 mmHg with no significant postural changes. The jugular venous pressure was normal at 2 cm above sternal angle and her carotid pulses were of low volume and delayed upstroke. The first heart sound (S1) was normal, however, S2 was soft and sin...