We investigated the importance of enterococcal aggregation substance (AS) and enterococcal binding substance (EBS) in rabbit models of Enterococcus faecalis cardiac infections. First, American Dutch belted rabbits were injected intraventricularly with 10 CFU and observed for 2 days. No clinical signs of illness developed in animals given AS EBS organisms, and all survived. All rabbits given AS ...

We investigated the importance of enterococcal aggregation substance (AS) and enterococcal binding substance (EBS) in rabbit models of Enterococcus faecalis cardiac infections. First, American Dutch belted rabbits were injected intraventricularly with 10(8) CFU and observed for 2 days. No clinical signs of illness developed in animals given AS- EBS- organisms, and all survived. All rabbits give...

background: sub-acute bacterial endocarditis (sbe) rarely presents with features of a small vessel vasculitis. patients with sbe can also develop multiple serological abnormalities including anca. in this report, we present a case of infective endocarditis mimicked anca associated glomerulonephritis.case presentation: a 57-year old male with a clinical picture of rapidly progressive renal failu...

Recent European guidelines have emphasized the association of vegetation size with embolic risk in endocarditis (1). On these grounds, left-sided vegetations >1 cm, and right-sided vegetations >2 cm are considered to be an indication for surgery. In this issue of iJACC, investigators from the MEDIC (Multicenter Electrophysiologic Device Cohort) registry report the importance of vegetation size ...

Patent ductus arteriosus (PDA) is an extracardiac left to right shunt. It should be corrected at an early age, but some patients may survive into adult life even without repair. Anesthetic management for adult patients with PDA poses many challenges for the anesthesiologist due to alterations in the cardiopulmonary physiology. We report successful anesthesia management of a case of an adult pat...

Background Transesophageal echocardiography is superior to transthoracic echocardiography in detecting left-sided valvular vegetations. There are no data on the value of transesophageal echocardiography in the diagnosis of infected transvenous permanent pacemakers. Methods and Results Transthoracic and transesophageal echocardiography was performed in 10 patients for whom there was clinical sus...