نتایج جستجو برای: lada
تعداد نتایج: 605 فیلتر نتایج به سال:
Star clusters are formed in molecular clouds which are believed to be the birth places of most stars. From recent observational data, Lada & Lada (2003) estimated that only 4% to 7% of the clusters embedded inside molecular clouds have survived. An important mechanism for the disruption of embedded (bound)-clusters is the dispersion of the parent cloud by UV radiation, stellar winds and/or supe...
OBJECTIVE Specific autoantibodies characterize type 1 diabetes in childhood but are also found in adult-onset diabetes, even when initially non-insulin requiring, e.g., with latent autoimmune diabetes (LADA). We aimed to characterize adult-onset autoimmune diabetes. RESEARCH DESIGN AND METHODS We consecutively studied 6,156 European diabetic patients attending clinics within 5 years of diagno...
This paper presents a formalism, LADA, aimed especially at the description of systems and situations which arise during the design and analysis of groupware. We are particularly interested in highly distributed systems and so LADA explicitly models entities (people and things) acting at different unconnected locations. It not only describes the behaviour of the computer software, but also the s...
Latent autoimmune diabetes in adults (LADA) according to various sources is from 4 12% of all cases type 2 mellitus (T2DM). Its uniqueness lies the simultaneous combination autoantibodies β-cells (characteristic T1DM) and possibility treatment with oral hypoglycemic drugs T2DM) for at least 6 months. This based on pathogenesis common T1DM T2DM — presence an reaction involvement adaptive innate ...
We explored the importance of the genetic markers microsatellite TNFa, HLA-DR3-DQ2, and DR4-DQ8 in diabetes mellitus. The studied groups comprised autoimmune type 1 (n = 63), nonautoimmune type 1 (n = 35), latent autoimmune diabetes in adults (LADA; n = 54), and nonautoimmune type 2 (n = 340) and these patients were compared to 117 healthy controls. HLA genotyping was done with polymerase chain...
STUDY OBJECTIVES The left anterior descending artery (LADA), particularly when the proximal segment of the vessel is involved, is a challenging area for percutaneous coronary interventions (PCIs); therefore, coronary artery bypass grafting is often considered and sometimes performed even in patients with single-vessel disease involving the LADA. This study compares mid-term results of LADA reva...
OBJECTIVE Patients with latent autoimmune diabetes in adults (LADA) express autoantibodies against the 65-kDa isoform of GAD (GADA). Intervention with recombinant human GAD65 formulated with aluminium hydroxide (GAD-alum) given twice subcutaneously to LADA patients at intervals of 4 weeks was safe and did not compromise β-cell function in a Phase II clinical trial. GADA affinity has been shown ...
OBJECTIVE We related organ-specific autoantibodies, including diabetes-associated autoantibodies (DAAs) and non-DAAs to systemic cytokines/chemokines in type 1 and type 2 diabetes. RESEARCH DESIGN AND METHODS From the European Action LADA (latent autoimmune diabetes in adults) cohort, patients with adult-onset type 1 diabetes (n = 80, of whom 50 had LADA and 30 had classic type 1 diabetes) an...
Autoimmunity is a well-known pathogenic component in type 1 diabetes (T1DM). The assumption that the pathogenesis of type 2 diabetes (T2DM) also encompasses autoimmune aspects is recognized increasingly, based on the presence of circulating autoantibodies against β cells, self-reactive T cells, but also on the glucose-lowering efficacy of some immunomodulatory therapies in T2DM. The identificat...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید