Isoflurane-anesthetized sheep were transfused with packed red blood cells (pRBCs) or diaspirin cross-linked hemoglobin (DCLHb) for treatment of intraoperative hemorrhage. A rapid 15-min hemorrhage with lactated Ringer (LR) infusion maintained filling pressure at baseline and reduced blood hemoglobin (Hb) to ~5 g/dl. Sheep received 2 g/kg Hb, DCLHb (n = 6), or pRBCs (n = 7); control group receiv...

METHOD: A total of 60 patients who were undergoing gastrointestinal surgery were randomized into a restrictive lactated Ringer’s group (n = 20), a goal-directed lactated Ringer’s group (n = 20) and a goal-directed hydroxyethyl starch group (n = 20). The goal-directed fluid treatment was guided by pulse pressure variation, which was recorded during surgery using a simple manual method with a Dat...

BACKGROUND Perioperative hemorrhage may depend on coagulation competence and this study evaluated the influence of coagulation competence on blood loss during cystectomy due to bladder cancer. METHODS Forty patients undergoing radical cystectomy were included in a randomized controlled trial to receive either lactated Ringer's solution or Dextran 70 (Macrodex ®) that affects coagulation compe...

INTRODUCTION There are limited data on the efficacy of early fluid resuscitation with third-generation hydroxyethyl starch (HES 130) in burn injury. Adverse effects of HES on survival and organ function have been reported. METHODS In this randomized, controlled, double-blind trial, 48 patients with severe burn injury were assigned to receive either lactated Ringer's solution plus 6% HES 130/0...

Objective: To compare the use of 6% Hetastarch with Lactated ringer's solution for prevention of hypotension after spinal anesthesia for transurethral resection of the prostate. Methods: In a randomized double blind study, 60 patients who underwent subarachnoid anesthesia for transurethral surgery were divided into two equal groups: group A were given Lactated ringer's solution and group B were...

AIM The aim of this study was to compare the efficacy and effects on acid-base and electrolyte status of several crystalloid fluids in 57 stranded juvenile loggerhead turtles. METHODS Within a rehabilitation program four different crystalloid fluids were administered (0.9% Na Cl solution; 5% dextrose + 0.9% Na Cl solutions 1:1; 0.9% Na Cl + lactated Ringer's solutions 1:1; lactated Ringer's s...

Banyaknya jumlah obat-obatan di rumah sakit seringkali meningkatkan risiko ketidaktepatan dalam manajemen persediaan farmasi, oleh karena itu, perlu dilakukan studi pengelolaan dan penggunaannya. Penelitian ini dimaksudkan untuk mengkaji efektivitas penggunaan obat Bima, Nusa Tenggara Barat. Adapun metode penelitian bersifat observasional retrospektif. Analisa data secara deskriptif. Evaluasi p...

Hypertonic solutions play an important role in the treatment of tissue edema. Following the induction of experimental vasogenic brain edema by occlusion of the common carotid arteries in eight rabbits, the effect of hypertonic lactated Ringer's solution (subjects), vs. isotonic lactated Ringer's solution (control), was studied on blood pressure, electrolyte (sodium, potassium, and calcium) ...