نتایج جستجو برای: lactamase oxa

تعداد نتایج: 15289  

Journal: :Journal of medical microbiology 2009
T W Boo F Walsh B Crowley

A 30 month prospective study of Acinetobacter species encountered in the Central Pathology Laboratory of St James's Hospital, Dublin, Ireland, was conducted to investigate the prevalence and molecular epidemiology of carbapenem resistance in such isolates. Acinetobacter genomic species 3 (AG3) was found to be the predominant Acinetobacter species (45/114, 39 %) in our institution. A total of 11...

2016
Taesoo Kwon Ji Woo Yang Sanghyun Lee Mi-ran Yun Won Gi Yoo Hwa Su Kim Jeong-Ok Cha Dae-Won Kim

The prevalence of Klebsiella pneumoniae coproducing carbapenemase metallo-β-lactamase 1 (NDM-1) and OXA-48 has been increasing globally since 2013. The complete genome of KP617 was sequenced and assembled into a circular chromosome and two plasmids. This sequence provides the genetic background for understanding the evolution of carbapenemase genes in K. pneumoniae KP617.

Journal: :Antimicrobial agents and chemotherapy 2004
Balázs Libisch Mária Gacs Károly Csiszár Mónika Muzslay László Rókusz Miklós Füzi

The first integron-borne metallo-beta-lactamase gene was isolated in Hungary. The bla(VIM-4) gene is located on a class 1 integron that also carries a novel bla(OXA)-like gene. The integron is harbored by a serotype O12 Pseudomonas aeruginosa strain and shows high structural similarity to integrons isolated in Greece and Poland.

2018
Ulrike Blaschke Evelyn Skiebe Michael Kaatz Paul G. Higgins Yvonne Pfeifer Gottfried Wilharm

Whole-genome sequencing of Acinetobacter sp. strain LoGeW2-3, isolated from the pellet of a white stork (Ciconia ciconia), reveals the presence of a plasmid of 179,399 bp encoding a CRISPR-Cas (clustered regularly interspaced short palindromic repeats and associated genes) system of the I-F type, and the chromosomally encoded novel class D beta-lactamase OXA-568.

Journal: :Antimicrobial agents and chemotherapy 2007
Yohei Doi Jennifer M Adams Kunikazu Yamane David L Paterson

Five highly amikacin-resistant Acinetobacter baumannii isolates were collected at a medical center in Pennsylvania. The aminoglycoside resistance was due to the production of the 16S rRNA methylase ArmA. Two of the isolates coproduced OXA-23 beta-lactamase and were highly resistant to carbapenems as well. The isolates were genetically closely related by pulsed-field gel electrophoresis.

2009
E.H. Takagi N. Lincopan V.C. Cassettari L.F. Passadore E.M. Mamizuka M.B. Martinez

Nineteen clonally related imipenem-resistant Acinetobacter baumannii isolates were recovered from eight intensive care unit patients. All isolates harboured bla OXA-51-like β-lactamase genes and showed the absence of 22 kDa fraction in outer membrane porin profile analysis. It suggests a combination of two mechanisms as responsible for carbapenem-resistant phenotypes.

Journal: :Antimicrobial agents and chemotherapy 2008
Thierry Naas Fatemeh Namdari Pierre Bogaerts Te-Din Huang Youri Glupczynski Patrice Nordmann

The genetic environment of the bla(OXA-18) gene encoding a peculiar clavulanic acid-inhibitable Ambler class D extended-spectrum beta-lactamase was determined from the prototype OXA-18-producing Pseudomonas aeruginosa MUS clinical isolate. An 8.2-kb genomic DNA fragment containing bla(OXA-18) was cloned from P. aeruginosa MUS. Although most oxacillinases are located in integrons, bla(OXA-18) la...

Journal: :Antimicrobial agents and chemotherapy 2006
Laurent Poirel Ludovic Cabanne Louis Collet Patrice Nordmann

A plasmid-encoded class II transposon element was identified in a carbapenem-resistant Pseudomonas putida isolate. Tn1332, closely related to Tn1331, harbored the metallo-beta-lactamase gene bla(VIM-2) in addition to four other antibiotic resistance genes, aacA4, aadA1, bla(OXA-9), and bla(TEM-1), and two novel insertion sequences, ISPpu17 and ISPpu18.

Journal: : 2022

<b>Aim:</b> This study aimed to determine the susceptibility of carbapenem-resistant Gr (-) bacilli isolated from various clinical infections antibiotics and identify genes causing carbapenem resistance their clonal relationships elucidate distribution in community and/or hospital-acquired strains.<br /> <b>Material methods:</b> In this study, antibiotic susceptibi...

2005
Jie Li Jason B. Cross Thom Vreven Samy O. Meroueh Shahriar Mobashery Bernhard Schlegel

An increasing number of proteins are being shown to have an N -carboxylated lysine in their structures, a posttranslational modification of proteins that proceeds without the intervention of a specific enzyme. The role of the carboxylated lysine in theseproteins is typically structural (hydrogen bonding or metal coordination). However, carboxylated lysines in the active sites of OXA-10 and OXA-...

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