BACKGROUND Lichen planus (LP) is a mucocutaneous inflammatory disease that affects multiple sites, including the skin, oral cavity, vulva, and vagina and can result in scarring and stricture formation. It has also been shown to cause lacrimal canalicular blockage in a series of patients attending an ophthalmology clinic. We describe a cohort of women with vulvovaginal LP who also had signs of l...

Observation is a simple and reliable tool with the clinician. The level of tears, position of puncta, lids and eyelashes should be noted. Obstruction of the tear drainage system can be acquired or congenital, it is important to rule out acquired causes of tearing such as corneal, lid or lash abnormalities. Lacrimal obstruction problems can be divided as related to upper (puncta to lacrimal sac)...

Here, we report an extremely rare case of acquired nasolacrimal duct obstruction caused by oncocytic carcinoma. A 64-year-old man presented to the hospital complaining of epiphora and left-side nasal obstruction. Ophthalmic and otolaryngology examination revealed a left lacrimal duct obstruction caused by a mass in the left nasal cavity and lacrimal drainage system. The mass was removed and con...

PURPOSE The main function of the lacrimal gland is to produce the most aqueous component of the tear film covering the surfaces of the cornea and the conjunctiva. Studies have been conducted that characterize the mixed fluid and protein secretion of isolated acini, but no methods have been developed to characterize lacrimal gland ductal cell (LGDC) secretion. Secretory mechanisms of ductal epit...

The isolated anomaly of imperforate lacrimal puncta was noted by Zehender (i867, I883). Similarly, blockage of the naso-lacrimal duct was noted by Crigler (1923) and Guerry and Kendig (1948), the anomaly usually being due to failure in canalization. The simultaneous occurrence of these two anomalies would appear to be very rare (Fig. i) and an extensive search of the literature has revealed onl...

The main objective of the present study was to prospectively evaluate long-term surgical success and safety in patients with nasolacrimal duct obstruction treated with a multidiode transcanalicular laser and bicanalicular silicone intubation stenting. 42 patients treated with transcanalicular laser dacryocystorhinostomy for nasolacrimal duct obstruction were prospectively enrolled. In all cases...

Chronic dacryocystitis results very often from obstruction to the nasolacrimal duct. It manifests as epiphora or watering of the eyes. The lacrimal sac gets expanded and also the wall of the sac gets thickened as a result of collection of mucopus due to obstruction of the nasolacrimal duct. Treatment of chronic dacryocystitis is by a surgical approach which consists of making an opening between...

PURPOSE To determine the source(s) of vitamin D in tear fluid and examine the expression of the endocytic proteins and putative vitamin D transporters megalin and cubilin in lacrimal and Harderian glands. METHODS Wild-type, heterozygous, and vitamin D receptor (VDR) knockout C57BL/6 mice were used, with a subset of knockout mice fed a replenishment diet for some studies. Mouse lacrimal and Ha...