Details of design and fabrication of a beamline RF load suited to accommodate SRF cavities are presented. Bonding an RF absorber to a heat sink is the key aspect of the load. Production loads have been effectively tested to 10.8 kW and operated in situ up to 3 kW.

The duocarmycins represent a new group of antitumor antibiotics produced by Streptomyces that bind to the minor groove of DNA. KW-2189 is a water-soluble semisynthetic derivative of duocarmycin B2, with significant activity in murine and human tumor models. We conducted a Phase I trial of KW-2189 in patients who had solid tumors that were refractory to standard chemotherapy or for whom no more ...

In order to manufacture smaller and more efficient electric motors an accurate prediction of the motor thermal performances at the design stage is a necessity. In addition, the thermal performance often needs to be analyzed when a motor is used in a different way to which it was originally designed for. An important example is the use of variable speed drives with induction motors designed for ...

The duocarmycins represent a new group of antitumor antibiotics produced by Streptomyces that bind to the minor groove of DNA. KW-2189 is a water-soluble semisynthetic derivative of duocarmycin B2, with significant activity in murine and human tumor models. We conducted a Phase I trial of KW-2189 in patients who had solid tumors that were refractory to standard chemotherapy or for whom no more ...

KW-5805, 5-[2-(diethylamino)ethyl]amino-5,11-dihydro[1]benzoxepino[3,4- b]pyridine trihydrochloride, is a new tricyclic compound with antiulcer activities. Its effect on stimulated gastric acid secretion was investigated in the perfused stomach of anesthetized rats. KW-5805 at 0.3-10 mg/kg, i.v., dose-dependently inhibited gastric acid secretion stimulated by 2-deoxy-D-glucose (2-DG). On the ot...

In recent years, the demand for the continuous wave (CW) fiber lasers of several kilowatts output power is increasing in use for metal materials processing. Fujikura group have all principal technologies required for constituting fiber lasers. We succeeded in commercializing the CW fiber laser of 4 kW output power by using those technologies. Our 4 kW CW fiber laser product has a high tolerance...

This paper is a sequel to [KW]. We develop here an intersection theory for manifolds equipped with an action of a finite group. As in [KW], our approach will be homotopy theoretic, enabling us to circumvent the specter of equivariant transversality. We give applications of our theory to embedding problems, equivariant fixed point problems and the study of periodic points of self maps.