The Biochemical Society is proud to offer the Krebs Memorial Scholarship commemorate life and work of Sir Hans Krebs, FRS (1900–1981). was a pioneer in study cellular respiration, notably earning Nobel Prize Physiology or Medicine 1953 for discovery citric acid cycle, originally published Journal. also recipient our own Frederick Gowland Hopkins Lecture (now known as Centenary Award) 1961.The F...

Lacunary polyoxometalates (POMs) are negatively charged metal–oxo clusters, formally obtained from plenary topologies via fragment removal. Owing to the removal, lacunary POMs archetypes rich in nucleophilic terminal oxo ligands, making them suitable for post-synthetic coordination with various heterometals. Trilacunary heteropolytungstates (hetero-POTs) based on bowl-shaped {W9O30} framework i...

Calcium antagonists have routinely been assumed to inhibit the contractions of arterial smooth muscle through block of membrane channels. The effects of nifedipine and diltiazem on contractions were examined in in vitro preparations of cattle coronary artery, one of the key therapeutic targets of calcium antagonists, to determine if alternate mechanisms of action are involved. Contractions elic...

Secretion of catecholamines (CA) from the isolated rat adrenal gland during and after perfusion with hypertonic Krebs bicarbonate solution was studied. Perfusion with hypertonic solution made by adding either 156 mM sodium chloride, choline chloride, arginine hydrochloride, sodium thiocyanate, or 312 mM sucrose had no effect on the spontaneous secretion of CA. The secretion evoked by splanchnic...