OBJECTIVE To examine the relation of radiographic features of osteoarthritis to knee pain in people with knees discordant for knee pain in two cohorts. DESIGN Within person, knee matched, case-control study. SETTING AND PARTICIPANTS Participants in the Multicenter Osteoarthritis (MOST) and Framingham Osteoarthritis studies who had knee radiographs and assessments of knee pain. MAIN OUTCOM...

OBJECTIVE To study the correlation between ankle and knee cartilage morphology to test the hypothesis that knee joint cartilage loss in gonarthritis can be estimated retrospectively using quantitative MRI analysis of the knee and ankle and established regression equations; and to test the hypothesis that sex differences in joint surface area are larger in the knee than the ankle, which may expl...

osteoarthritis (oa) a common disease of aged population and one of the leading causes of disability. incidence of knee oa is rising by increasing average age of general population. age, weight, trauma to joint due to repetiting movements in particular squatting and kneeling are common risk factors of knee oa. several factors including cytokines, leptin, and mechanical forces are pathogenic fact...

both vitamin d deficiency and quadriceps muscle weakness are associated with knee osteoarthritis (koa) and pain. the aim of this study was to determine the restorative effect of vitamin d deficiency on pain and quadriceps muscle strength in knee osteoarthritis. patients with koa aged≥30 years, the presence of knee pain for at least one month or longer and serum 25-hydroxyvitamin (25-ohd) defici...

BACKGROUND Quadriceps muscle strengthening is a common goal in the management of knee osteoarthritis. In healthy knees, strength protects against new osteoarthritis. In arthritic knees, greater strength may protect joints and thereby delay osteoarthritis progression. Alternatively, in certain joint environments, such as malalignment or laxity, greater strength may translate into damaging joint ...

A randomized, single-blind, placebo-controlled trial was carried out in 62 patients (30 with osteoarthritis of the hip, 32 with osteoarthritis of the knee) to examine the efficacy of glycosaminoglycan-peptide complex in the treatment of osteoarthritis. Patients received 8-week courses of trial medication, each consisting of intramuscular injections of 3 x 2 ml ampoules per week, alternating wit...

BACKGROUND AND PURPOSE Pain sensitization may be one of the reasons for persistent pain after technically successful joint replacement. We analyzed how pain sensitization, as measured by quantitative sensory testing, relates preoperatively to joint function in patients with osteoarthritis (OA) scheduled for joint replacement. PATIENTS AND METHODS We included 50 patients with knee OA and 49 wi...

BACKGROUND Self-reported knee joint instability compromises function in individuals with medial knee osteoarthritis and may be related to impaired joint mechanics. The purpose of this study was to evaluate the relationship between self-reported instability and the passive varus-valgus mechanical behaviour of the medial osteoarthritis knee. METHODS Passive varus-valgus angular laxity and stiff...

INTRODUCTION Osteoarthritis of the knee affects millions of people. Elastic knee sleeves aim at relieving symptoms. While symptomatic improvements have been demonstrated as a consequence of elastic knee sleeves, evidence for biomechanical alterations only exists for the sagittal plane. We therefore asked what effect an elastic knee sleeve would have on frontal plane gait biomechanics. METHODS...

[Purpose] The aims of the present study were to investigate the most suitable location for vibroarthrography measurements of the knee joint to distinguish a healthy knee from knee osteoarthritis using Wavelet transform analysis. [Subjects and Methods] Participants were 16 healthy females and 17 females with severe knee osteoarthritis. Vibroarthrography signals were measured on the medial and la...