The activity of RNA-dependent RNA polymerase of several influenza viruses is stimulated by guanosine. Depending upon the virus strain used, the stimulation of initial reaction rate is up to 10-fold. 5'-GMP, 3',5'-cyclic GMP, and 5'-GDP show lesser stimulation effects. No other nucleosides of 5'-NMPs stimulate, but the dinucleoside monophosphates GpG and GpC show large stimulations. We present e...

Stimulation of mitochondrial respiration by physiological concentrations of Ca2+ was studied to determine which components of oxidative phosphorylation are affected by Ca2+. The kinetic dependence of the respiratory chain, phosphorylation subsystem and proton leak on the mitochondrial membrane potential in isolated rat heart mitochondria respiring on 2-oxoglutarate or succinate was measured at ...

In this note, we prove the generic Kobayashi volume measure hyperbolicity of singular directed varieties (X,V ), as soon as the canonical sheaf KV of V is big in the sense of Demailly.

Activated DMA-directed DNA synthesis catalyzed by Rauscher leukemia virus (RLV) and other type C mammalian retroviral DNA polymerases is uniquely stimulated by biologically active polyamines. Cationic trypanocides may act as antagonists of polyamine function. As described here, several cationic trypanocides stimulate RLV polymerase-catalyzed DNA-directed DNA synthe sis at concentrations signifi...

the aim of this investigation is to compare the effect of applying two transcutaneous electrical nerve stimulation (tens) current with different frequencies (2 hz & 100 hz) on hoffmann reflex recorded from gastrosoleus muscle of healthy people. forty female subjects between 20 to 30 years of age were participated in this quasi-experimental design. twenty of them were exposed to the 100 hz curre...

background: motor function impairment occurs in approximately two-thirds of patients with subcortical stroke. repetitive transcranial magnetic stimulation (rtms) is a noninvasive technique for modulating cortical excitability. objectives: the present study was designed for assessing the efficacy of high-frequency rtms (5 hz) on ipsilesional primary motor cortex in patients with subcortical stro...

AIM The objective was to characterize cross-bridge kinetics from the cytoplasmic calcium ion concentration ([Ca2+](i)) and the left ventricular pressure (LVP) in the early-stage diabetic rat heart under baseline conditions and upon beta-adrenergic stimulation. METHODS Four weeks after the induction of diabetes in rats by the injection of streptozotocin, the hearts were perfused according to L...

E-learning is popularized so fast and Collaborative Learning (CL) becomes so important an instructional strategy. There are huge Group Session (GS) texts needed to be analyzed to evaluate CL, thus the automatic or semi-automatic methods of analyzing the GS texts become very important. In this paper we present a method called Interaction Analysis depended on Knowledge Extraction (IAKE) to analyz...

We discuss various properties of the ground state of a Bose-condensed dilute gas confined by an external potential. We devote particular attention to the role played by the interaction in determining the kinetic energy of the system and the aspect ratio of the velocity distribution. The structure of the wave function near the classical turning point is discussed and the drawback of the Thomas-F...

Chemoattractants added to cells of the cellular slime mold dictyostelium discoideum induce a transient elevation of cyclic GMP levels, with a maximum at 10 s and a recovery of basal levels at approximately 25 s after stimulation. We analyzed the kinetics of an intracellular cGMP binding protein in vitro and in vivo. The cyclic GMP binding protein in vitro at 0 degrees C can be described by its ...