Congenital Hepatic Fibrosis (CHF) is a rare disease that affects both the liver and kidneys.  Congenital hepatic fibrosis (CHF) is an autosomal recessive inherited malformation defined pathologically by a variable degree of periportal fibrosis and irregularly shaped proliferating bile ducts. Affected individuals also have impaired renal function, usually caused, in children and teenagers, by an...

incidence of diabetes is increasing in developing countries as well as iran. half of the patients are not aware of their disease so screening of diabetes is necessary. lifestyle changes in society, high-saturated fat diet and decreased physical activity are the factors that influence the growing rate of diabetes in iran.1 the need for addressing type 2 diabetes has been clarified for family phy...

Pregnancy in end stage renal disease women who are on Hemodialysis has been considered a challenging event for both mother and fetus. Generally, outcomes of pregnancy in patients with end-stage renal disease (ESRD) have been considered to be extremely poor, and pregnancy in this group of patients is rather scarce. The frequency of conception is ranged from 0.3% per year in Belgium to 1.4% per y...

Objective(s):MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression. They have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (CKD). In the present study, we elucidated the role of microR...

autosomal dominant polycystic kidney disease (adpkd) is the most common form of inherited kidney disease that results in renal failure. pkd currently has no causative therapy. however, some treatment options are available, ranging from symptomatic therapy to delaying the onset of end-stage renal failure. early diagnosis of adult polycystic kidney disease is vital in order to prevent its complic...