OBJECTIVES Tracheal intubation of ICU patients is frequently associated with severe hypoxemia. Although noninvasive ventilation reduces desaturation during intubation of severely hypoxemic patients, it does not allow for per-procedure oxygenation and has not been evaluated in mild-to-moderate hypoxemic patients for whom high-flow nasal cannula oxygen may be an alternative. We sought to compare ...

Postoperative atelectasis should be avoided in surgical patients with impaired pulmonary function. Nasal high-flow (NHF) therapy delivered by the Optiflow™ system (Fisher & Paykel Healthcare Ltd., Auckland, New Zealand) is a new, simple device that supplies heated and humidified oxygen gas at >30 L/min via a large-bore nasal cannula. We herein describe a case in which respiratory support with N...

L’oxygénothérapie à haut débit est un dispositif qui permet de délivrer gaz par voie nasale. Ce réchauffé et humidifié sa fraction inspirée en oxygène réglable. Les effets physiologiques sont nombreux : lavage l’espace mort anatomique, stabilité la oxygène, préservation muqueuse clairance mucociliaire. Ces expliquent les bénéfices cliniques constatés amélioration des échanges gazeux, baisse du ...

RATIONALE Obstructive sleep apnea syndrome is due to upper airway obstruction and is associated with increased morbidity. Although continuous positive airway pressure efficaciously treats obstructive apneas and hypopneas, treatment is impeded by low adherence rates. OBJECTIVES To assess the efficacy on obstructive sleep apnea of a minimally intrusive method for delivering warm and humidified ...

Despite the absence of clinical safety data, heated, humidified high-flow nasal cannula (HHFNC) therapy is increasingly being used as an alternative to positive-pressure ventilation in pediatrics. This use of HHFNC is "off label" because the US Food and Drug Administration's approval for these devices was only for air humidification and not as a modality to provide positive distending pressure....

The delivery of oxygen, whether as treatment for hypoxemia or supportive adjunct in shock or surgery, is a mainstay of modern medical therapy, yet conventional oxygen therapy, delivered either by nasal cannula or face mask, remains limited by the high oxygen delivery demand of the acute and critically ill patient. By employing a tight fitting mask or mask-like interface, noninvasive ventilation...

BACKGROUND During sedation for upper gastrointestinal endoscopy, oxygen delivery via a nasal cannula is often necessary. However, the influences of the oxygen delivery route and breathing pattern on the F(IO2) have not been thoroughly investigated. The aim of this simulation study was to investigate the difference in the F(IO2) with a pharyngeal cannula versus nasal cannula during high- or low-...

Drug administration via high flow nasal cannula (HFNC) has been described in pediatrics but the amount of albuterol delivery with an HFNC is not known. The purpose of this study is to quantify aerosol delivery with heliox and oxygen (O(2)) in a model of pediatric ventilation. A vibrating mesh nebulizer (Aeroneb Solo, Aerogen) was placed on the inspiratory inlet of a heated humidifier and heated...