Abstract This paper applies a new approach to the identification of discourses, based on Multiple Correspondence Analysis (MCA), study discourse variation over time. The MCA keywords deals with major issue use identify discourses: allocation individual multiple discourses. Yet, as this demonstrates, also allows us observe in prevalence discourses texts patterns keyword co-occurrence. Metadata c...

Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease characterized by progressive degeneration of both upper and lower motor neurons, resulting in paralysis eventually leads to death from respiratory failure typically within 3 5 years symptom onset. The aim this work was predict the pharmacokinetics identify unique protein targets that are associated with potential ...

Authors are requested to select key words from the following list. You may use plurals and adjectives for combinations like absolute pupillary response, centrifugal optic nerve, inter blobs, etc. If key words are needed which do not appear in this list, please underline them. For animal classification the Latin nomenclature should be used. p-mechanism A-scan a-wave aberration absolute absorptio...

ETHNOPHARMACOLOGICAL RELEVANCE Peganum harmala is used in traditional medicine to treat a number of diseases including cancer. Our preliminary studies show that the alkaloidal extract of PH seed is cytotoxic to several tumor cell lines in vitro and has antitumor effect in a tumor model in vivo. The present investigation was aimed at extending our previous studies in identifying the components i...

The effects of the South American psychotropic beverage ayahuasca on subjective and cardiovascular variables and urine monoamine metabolite excretion were evaluated, together with the drug's pharmacokinetic profile, in a double-blind placebo-controlled clinical trial. This pharmacologically complex tea, commonly obtained from Banisteriopsis caapi and Psychotria viridis, combines N,N-dimethyltry...