We evaluated the expression and DNA binding activity of nuclear factor (NF)-scB subunits in human peripheral blood monocytes and in monocyte-derived macrophages (MDMs). Constitutive DNA binding activity consisting of p50 homodimers was detected in nuclear extracts from both cell types. An additional complex composed of p50/ReIA(p65) heterodimers appeared only in nuclear extracts from 7-day MDMs...

Nuclear factor-kappaB (NF-kB) is a key inflammatory transcription factor expressed frequently in tumors. Numerous studies have investigated the correlation between NF-kB expression and prognosis in solid tumors, but the conclusions are still in contradiction. Here, we conduct a meta-analysis to explore the overall association of NF-kB overexpression and survival in human solid tumors. Pubmed an...

A numerical multiple crack interaction model was developed to simulate the failure process in brittle solids containing significant populations of flaws. The model, which is 2D, allows for the growth of microcracks on a regular array of potential crack sites. Individual cracks may be oriented vertically, horizontally or at 450 to the sample axes. Quasi-static equilibrium equations are expressed...

The generation of referring expressions (GRE), an important subtask of Natural Language Generation (NLG) is to generate phrases that uniquely identify domain entities. Until recently, many GRE algorithms were developed using only simple formalisms, which were taylor made for the task. Following the fast development of ontology-based systems, reinterpretations of GRE in terms of description logi...

Introduction The advancement of the Internet technology has increased the need for distributed, concurrent, heterogeneous and dynamic application systems. Agent technology is a new paradigm suitable for developing such systems that situates and operates in a dynamic and heterogeneous environment. What exactly is an agent? To date, there is no widely accepted definition of what an agent is. In t...

In contrast to the usual Lipschitz seminorms associated to ordinary metrics on compact spaces, we show by examples that Lipschitz seminorms on possibly non-commutative compact spaces are usually not determined by the restriction of the metric they define on the state space, to the extreme points of the state space. We characterize the Lipschitz norms which are determined by their metric on the ...

In the past 20 years, AI researchers in knowledge representation (KR) have implemented over 50 frame knowledge representation systems (FRSs). KR researchers have explored a large space of alternative FRS designs. This paper surveys the FRS design space in search of design principles for FRSs. The FRS design space is de ned by the set of alternative features and capabilities | such as the repres...