This entry explores the innovative use of lasers in non-surgical treatment periodontitis, shedding light on advantages, effectiveness, and limitations this approach. There has been a massive eruption innovations technologies to assist periodontal diseases over past 30 years. The opened new horizons possibilities that can enhance treatments. However, their is not always based validated concepts ...

The retinal pigment epithelium lies at the interface between the neural retina and the choriocapillaris where it forms a blood-retinal barrier. Barrier function requires a polarized distribution of plasma membrane proteins and 'tight' tight junctions. During chicken embryogenesis, these features develop gradually. Although terminal junctional complexes are established by embryonic day 4, the di...

The intercellular junctions of the anterior ciliary and iridial epithelia of the inflamed rabbit eye were examined by use of an ultrastructural tracer, conventional electron microscopy, and the freeze-fracture technique. In normal control eyes, intravascularly injected horseradish peroxidase was prevented from entering the posterior chamber by the zonulae occludentes of the nonpigmented ciliary...

PURPOSE Gap junctions between epithelial cells are essential for normal lens growth. In mice, knockout of Cx50 or targeted replacement of Cx50 with Cx46 (knockin) caused smaller lenses because of decreased epithelial cell proliferation. However, it remains unclear whether Cx50 functionally contributes to lens epithelial coupling during maximal proliferation on postnatal day 2 (P2) and P3. To de...

Interimplant papillae are critical to achieving esthetic implant-supported restorations in the maxillary esthetic zone. Stable papillary anatomy, however, depends upon a stable volume of underlying crestal bone for support. Multiple studies have documented a critical interimplant distance of 3 mm, under which crestal bone resorption occurs. The current preclinical proof-of-principle canine stud...

Under conditions of homeostasis, dynamic changes in the length of individual adherens junctions (AJs) provide epithelia with the fluidity required to maintain tissue integrity in the face of intrinsic and extrinsic forces. While the contribution of AJ remodeling to developmental morphogenesis has been intensively studied, less is known about AJ dynamics in other circumstances. Here, we study AJ...

abstract   background: to evaluate proximal junctional segment changes in adolescent idiopathic scoliosis(ais) the posterior spinal fusion and also instrumentation also and finding of probable risk factors, were all considered in this study.   methods: we retrospectively reviewed radiographs of 121 consecutive patients who underwent posterior spinal fusion for ais from t3 or below, with a mean ...

BACKGROUND AND OBJECTIVES The corneal epithelium provides a protective barrier against pathogen entrance and abrasive forces, largely due to the intercellular junctional complexes between neighboring cells. After a prescribed duration at the corneal surface, tight junctions between squamous surface cells must be disrupted to enable them to desquamate as a component of the tissue homeostatic ren...