OBJECTIVES The aims of this study were to model jointly the incidence rates of six smoking related cancers in the Yorkshire region of England, to explore the patterns of spatial correlation amongst them, and to estimate the relative weight of smoking and other shared risk factors for the relevant disease sites, both before and after adjustment for socioeconomic background (SEB). METHODS Data ...

OBJECTIVES Recent studies have suggested the occurrence patterns and related diet factor of esophagus cancer (EC) and gastric cancer (GC). Incidence of these cancers was mapped either in general and stratified by sex. The aim of this study was to model the geographical variation in incidence of these two related cancers jointly to explore the relative importance of an intended risk factor, diet...

introduction: knee joint osteoarthritis is one of the most prevalent musculoskeletal problems in adult population, which cause pain and functional limitations. involvement of medial compartment is almost 10 times more common than lateral compartment, which results in varus deformity among patients with medial compartment osteoarthritis of knee joint. main objectives in the treatment of knee joi...

Self-reconfiguration of robotic manipulators under joint failure can be achieved via fault-tolerance strategies. Faulttolerant manipulators are required to continue their endeffector motion with a minimum velocity jump, when failures occur to their joints. Optimal fault tolerance of the manipulators requires a framework that can map the velocity jump of the end-effector to the compensating join...

Introduction: Measurement of proton transverse relaxation time (T2) can be used to detect pathological changes in tissue for a variety of clinical applications, including identification of edema and iron overload. The most widely used T2 mapping pulse sequence is the Carr-Purcell-Meiboom-Gill (CPMG) sequence [1,2]. For body MRI, however, a CPMG pulse sequence is typically performed with navigat...

behçet’s disease (bd) is a multisystem disorder with potential ability to influence the pregnancy outcome and pregnancy is associated with several physiologic alterations which can lead to potential changes in the course of the disease. we studied 77 pregnancies in 69 women with bd. the disease activity was calculated by two methods for three periods of before, during and after pregnancy to eva...

Chikungunya virus (CHIKV) and related alphaviruses cause epidemics of acute and chronic musculoskeletal disease. To investigate the mechanisms underlying the failure of immune clearance of CHIKV, we studied mice infected with an attenuated CHIKV strain (181/25) and the pathogenic parental strain (AF15561), which differ by five amino acids. Whereas AF15561 infection of wild-type mice results in ...