introduction: endothelium and smooth muscle dysfunction are the most important complications of diabetes. in type 1 diabetic patients, absence of insulin leads to vasoconstriction and lower skin blood perfusion. release of some mediators by endothelium which is induced by insulin causes vasodilation, but the exact mechanism of insulin vasodilatory effect is not detected properly. at present stu...

Objective(s): One applications of nanotechnology is in the area of medicine which is called nanomedicine. Primary instruments in nanomedicine can help us to detect diseases and used for drug delivery to inaccessible areas of human tissues. An important issue in simulating the motion of nanoparticles is modeling blood flow as a Newtonian or non-Newtonian fluid. Sometimes blood flow is simulated ...

BACKGROUND The endocannabinoid system has been shown to reduce inflammatory flares and pain in rodent models of arthritis. A limitation of endocannabinoids is that they are rapidly denatured by hydrolysing enzymes such as fatty acid amide hydrolase (FAAH) which renders them physiologically inert. Osteoarthritis (OA) is primarily a degenerative joint disease; however, it can incorporate mild inf...

The eVect of intensive exercise on disease activity in rheumatoid arthritis (RA) is an interesting one. Although we would not dispute that such exercise does indeed have a beneficial eVect on parameters of disease activity, we wish to propose an alternative hypothesis as to its mechanism. In particular, we would argue that the eVect of raised intraarticular pressure on synovial blood flow durin...

In this investigation, a mathematical model for studying oscillatory flow of blood in a stenosed artery under the influence of transverse magnetic field through porous medium has been developed. The equations of motion of blood flow are solved analytically. The analytical expressions for axial velocity, volumetric flow rate, pressure gradient, resistance to blood flow and shear stress have been...

in the present study, the nonlinear model of non-newtonian blood flow in cosine-shape stenosed elastic artery is numerically examined. the model is carried out for axisymmetric, two-dimensional and fully developed blood flow. the vessel wall is assumed to be have time-dependent radius that is important factor for study of blood flow. the cosine-shape stenosis convert to rigid artery by using a ...

Previous studies have shown that electrical stimulation (ES) increases blood flow, but the exact mechanisms are not clear. The present study was designed to clarify some of the underlying mechanisms involved in this phenomenon. White adult rabbits Lt.-6 months old were used. Animals were anesthetized by sodium pentobarbital (40 mg/kg, IV) and skin blood flow in the thoracic back was recorde...

introduction:amphetamines are central nervous system (cns) stimulant substances and amphetamine abuse is considered a growing problem in our country. previous studies revealed destructive effects of amphetamines on metabolism, perfusion and structure of brain. the aim of current study was evaluating regional cerebral blood flow (rcbf) disturbances in methamphetamine (ma) abusers using brain per...