The gastric polyps are rare as compared to the colonic polyps. Multiple gastric polyps are seen in association with other polyposis syndromes like juvenile polyposis, Gardner's syndrome, the Peutz-Jeghers syndrome and the Cronkhite-Canada syndrome. Diffuse gastric polyposis is a rare entity and only few cases have been reported. The mode of treatment is surgery, either total or near total gastr...

Introduction: Peutz-Jeghers syndrome (PEUTZ-JEGHERS SYNDROME; PJS; OMIM#175200) is hereditary tumor and characterized by the occurrence of hamartomatous polyps gastrointestinal tract, melanocytic pigmentation skin mucous membranes, as well a high predisposition to malignant tumors various locations. Despite fact that clinical features PJS are currently understood, nature variability in phenotyp...

Peutz-Jeghers syndrome (PJS) is an hereditary syndrome characterized by gastrointestinal polyposis and mucocutaneous pigmentation. PJS patients are at increased risk of developing various cancers, especially of the gastrointestinal and gynaecological tracts. Colonic adenocarcinoma is one of the more common tumours that occur in PJS. We report a young lady presenting with a large ovarian tumour,...

Laugier-Hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. We present the case of a 63-year-old female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7-year history of hyperpigmentation in several fingernails. Laugier-Hunziker syndrome was diagnosed based on the clinical features...

Cutaneous hyperpigmentation may be caused by a number of diseases, such as Addison’s disease, scleroderma, haemochromatosis, Peutz-Jeghers syndrome, lichen planus, and adverse reactions to some medications such as oral contraceptives, cyclophosphamide, chloroquine, minocycline, bleomycin, ketoconazole and methyldopa (1). Hyperpigmentation of the tongue, face and body skin is a rare adverse effe...