A case of 50 years of age, male with sporadic Creutzfeldt Jakob Disease (sCJD) is reported. Patient had dementia, behavioural abnormalities, unsteady gait and myoclonic jerks. Magnetic resonance imaging (MRI) brain T2 weighted and Fluid Attenuated Inverse Recovery (FLAIR) images showed abnormally increased signal intensity in caudate nucleus and putamen. Scalp electroencephalogram (EEG) reveale...

Three cases of probable iatrogenic transmission of Creutzfeldt-Jakob disease by neurosurgery are detailed together with a cluster of three cases in Eastern England possibly connected by dental procedures, and the development of Creutzfeldt-Jakob disease in a patient who had been in social contact with a familial case.

Creutzfeldt-Jakob Disease (CJD) is a rare, incurable, fatal degenerative disease of the central nervous system. The majority of cases occur between the ages of 50 and 75 years, although patients as young as 10 years and as old as 80 years have been reported. The disease is not geographically limited and has been reported from over 50 countries around the world. CJD affects both males and female...

no. EU056810) and 1986 (accession nos. HM234642 and GU131843) epidemics in Burkina Faso. Strains of DENV-2 from the 2005 epidemic in Ghana (accession no. EU005258) shared 95% identity with that of the patient reported here. Phylogenetic analysis indicated that the dengue virus genome sequence in this case is highly homologous with recent strains in Africa, especially from the 2016, 1986, and 19...

Sporadic: about 85% of case. [4] It is rare at around one case per million population per year. It is found throughout the world, and is thought to be due to a spontaneous mutation of the prion protein. It is not transmitted. Hereditary: a little under 15% of cases. This variant occurs in family clusters with a dominant pattern of inheritance. [4] Iatrogenic CJD: may be transmitted by instrumen...

REPORTING INFORMATION  Class B2: Report by the end of the business week in which the case or suspected case presents and/or a positive laboratory result to the local public health department where the patient resides. If patient residence is unknown, report to the local public health department in which the reporting health care provider or laboratory is located.  Reporting Form(s) and/or Mec...

Starting out from a case report about a 84-year-old woman changing from absolute inconspicuousness to complete senile dementia within a few months, the authors present a not very well known neuropsychiatric disorder: the Jakob-Creutzfeldt disease. In short, historical, morphological and symptomatological aspects and laboratory findings are discussed, and it is shown that the complex problem of ...

Accessible online at: www.karger.com/ene Creutzfeldt-Jakob disease (CJD) is a transmissible spongiform encephalopathy. It is characterised pathologically by neuronal loss, spongy changes in the grey matter and an astrocytosis, and clinically by rapidly progressing dementia, pyramidal and extrapyramidal disease with myoclonus and triphasic discharges in the electroencephalogram. This dreaded fat...

Sporadic: about 85% of case. [4] It is rare at around one case per million population per year. It is found throughout the world, and is thought to be due to a spontaneous mutation of the prion protein. It is not transmitted. Hereditary: a little under 15% of cases. This variant occurs in family clusters with a dominant pattern of inheritance. [4] Iatrogenic CJD: may be transmitted by instrumen...