Analyses of complete genomes indicate that insertion sequences (ISs) are abundant and widespread in hyperthermophilic archaea, but few experimental studies have measured their activities in these hosts. As a way to investigate the impact of ISs on Sulfolobus genomes, we identified seven transpositionally active ISs in a widely distributed Sulfolobus species, and measured their functional proper...

Input-to-State Stability (ISS) and the ISSLyapunov function have proved to be useful tools for the analysis and design of nonlinear systems in a variety of contexts. Motivated by the fact that many feedback control laws, such as model predictive control or event-based control, lead to discontinuous discrete-time dynamics, we investigate ISS-Lyapunov functions for such systems. ISS-Lyapunov func...

OBJECTIVE We sought to identify differentially expressed genes in human in stent stenosis (ISS) to provide insights into the mechanism of disease. METHODS AND RESULTS Using representation difference analysis, we examined differential gene expression between cultured normal human medial vascular smooth muscle cells (VSMCs) and cells from primary atherosclerotic plaques or ISS sites. Specific g...

Insertion sequences (ISs) are ubiquitous and abundant mobile genetic elements in prokaryotic genomes. ISs often encode only one protein, the transposase, which catalyzes their transposition. Recent studies have shown that transposases of many different IS families interact with the β sliding clamp, a DNA replication factor of the host. However, it was unclear to what extent this interaction lim...

We investigated the associations of injury severity scores (ISSs) with the mean platelet volume, the serum levels of two interleukins (IL1β and IL6), and the serum levels of tumour necrosis factor-α (TNFα) and C-reactive protein (CRP). We sought to identify biochemical parameters that could be used as components of a new biochemical parameter-based ISS system. The levels of CRP, TNFα, IL1β, and...

The increased serum survival gene iss has long been recognized for its role in extraintestinal pathogenic Escherichia coli (ExPEC) virulence. iss has been identified as a distinguishing trait of avian ExPEC but not of human ExPEC. This gene has been localized to large virulence plasmids and shares strong similarities with the bor gene from bacteriophage lambda. Here, we demonstrate that three a...

The MASIV 5 GHz VLA flat-spectrum radio source variability survey of the northern sky has discovered that more than half of its 475 targets exhibited interstellar scintillation (ISS) at one or more of the four survey epochs. vVe present the first results of the spectroscopic identifications of the sample. For 253 sources the spectroscopic identification is obtained and evaluated from the litera...

Immunostimulatory sequences (ISS) are short oligonucleotides containing unmethylated cytosine-phosphate-guanine (CpG) dinucleotides that stimulate innate immune responses through Toll-like receptor-9 on B cells and plasmacytoid dendritic cell (PDC) precursors. The anti-inflammatory cytokine interleukin (IL)-10 is predicted to be a potent inhibitor of many of the activities described for ISS, an...

BACKGROUND This study validates the accuracy of the Injury Severity Score (ISS) and the New Injury Severity Score (NISS) systems for prediction of need intubatin (NI), need mechanical ventilation (NMV), and duration of mechanical ventilation (DMV) in intensive care unit (ICU) trauma patient admissions. METHODS One-hundred ten trauma patients were included in this prospective cohort study. The...

In this paper the input-to-state stability (iss) property is studied for discrete-time nonlinear systems. We show that many iss results for continuoustime nonlinear systems in earlier papers (Sontag, 1989; Sontag, 1990; Sontag and Wang, 1996; Jiang et al., 1994; Coron et al., 1995) can be extended to the discretetime case. More precisely, we provide a Lyapunov-like sufficient condition for iss,...